DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17633 and CG4408

DIOPT Version :9

Sequence 1:	NP_609310.2	Gene:	CG17633 / 34297	FlyBaseID:	FBgn0032144	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_651141.2	Gene:	CG4408 / 42762	FlyBaseID:	FBgn0039073	Length:	479	Species:	Drosophila melanogaster

Alignment Length:	417	Identity:	158/417 - (37%)
Similarity:	243/417 - (58%)	Gaps:	14/417 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 ASASVSAERVRYDNYRMYKVNSENAKQLEVLKDLEGSSDSIMFLDGVHLVGADIQIIVAPHKVPD 80
            |:.||.|   |||:.|:|:|...:.:.:.:.:.||.:|||..|:......|..:.|:|...||.|
  Fly    73 AADSVQA---RYDHTRIYQVELASEEHVRLFQALEQASDSCSFMGHARQPGQKLTIMVTGAKVAD 134

  Fly    81 FLEILGKSEIKYELQSRDVQKSLDEIDEKVAIKGRATTAYNWAQYYELDDTYAWLQSLAQTNPGV 145
            |.:::....:.:.:.:.:.|..:|....:||.:......::|.:|:.|:...|||:.||:|:|.|
  Fly   135 FDDLVHSYNVTHRVLNYNFQALIDANYLEVAPEDTKPEEFDWKRYHPLESINAWLKKLAETHPEV 199

  Fly   146 VTLIEGGKTYQGRSILGVKITKGGETINGKAKPGIFLEAGIHAREWIAPAAATFIINQLLTSEVE 210
            : |:|.|.:.|||.||||:|....|.     :..:|:|:|||||||||||.||:||:||:.|:..
  Fly   200 L-LVELGVSAQGRPILGVQIAFDNEN-----RTTVFVESGIHAREWIAPATATYIIDQLVNSKDS 258

  Fly   211 NIKELAENYTWYVLPHANPDGYVYTHTTNRLWRKTRTPYGSCFGADPNRNWGFHWNEVGASSSAC 275
            .::.||.:..||:.|..|||||.||...:|:|||.|..:|.|.|.|.|||:.||||..|||...|
  Fly   259 AVQALARSQRWYIFPTVNPDGYQYTFKGDRMWRKNRALFGICRGVDLNRNFPFHWNVTGASGDPC 323

  Fly   276 SDTYAGPSAFSEIETLSLSKFIEGL--KGKVQLYLSLHAYSQYLLYPYGHTSDLPDNVADFEKVF 338
            ...|:||||.||:||..:.:||...  ..:::.::|||:|||.:::||||:::..||..|...:.
  Fly   324 RYDYSGPSAASEVETQRMIEFIRHRVESERIRTFISLHSYSQMIMFPYGHSAERVDNYHDLTDIG 388

  Fly   339 DASIAAVNKRYGTTYTGGNIYDAIYPAAGASVDWAYGTQDVRMAFCYELR-PSSTSYLTGFKLPA 402
            ..:...:....|..|..|:||:.|||::|.|.|||:|...:.:.|.|||| |:.:..|  |.|.|
  Fly   389 KLAANKIKDVSGRIYKSGSIYETIYPSSGGSKDWAHGQLKIPITFSYELRGPADSEDL--FILSA 451

  Fly   403 EQIVPASEELLDSIVAMATEVKSLGYF 429
            ::|.|.:.|...||..:..|....||:
  Fly   452 KEIEPTAAEAFASIQTIVQEAGKRGYY 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17633	NP_609310.2	MpaA	7..374	CDD:225421	138/359 (38%)
		Propep_M14	34..105	CDD:280416	15/70 (21%)
		M14_CP_A-B_like	125..423	CDD:199844	127/300 (42%)
CG4408	NP_651141.2	Propep_M14	88..159	CDD:280416	15/70 (21%)
CG4408	NP_651141.2	M14_CP_A-B_like	179..472	CDD:199844	127/300 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467027
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	239	1.000	Inparanoid score	I2114
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm4737
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
	11	10.800