DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17633 and CG8560

DIOPT Version :9

Sequence 1:	NP_609310.2	Gene:	CG17633 / 34297	FlyBaseID:	FBgn0032144	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_001261516.1	Gene:	CG8560 / 38830	FlyBaseID:	FBgn0035781	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	425	Identity:	160/425 - (37%)
Similarity:	239/425 - (56%)	Gaps:	23/425 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LFALLAIVASASVSAERVRYDNYRMYKVNSENAKQLEVLKDLEGSSDSIMFLDGVHLVGADIQII 72
            |||::.::||.:::.|  .||.|::|.:|:.||.:.::|..|.| :::..|.|....:.|..:::
  Fly     4 LFAVVLLLASVALAVE--NYDGYKIYDINARNAFEKQLLLRLSG-NEAYDFFDLPRSLDASSRVM 65

  Fly    73 VAPHKVPDFLEILGKSEIKYELQSRDVQKSL-DEIDE----KVAIKGRATTAYNWAQYYELDDTY 132
            |.|.....|..:|.|..:.|.:.:.:..:|| .|.||    ::.....|..:.::..::...:..
  Fly    66 VKPEDQEGFEHLLEKYGVNYSVINENFGESLRQERDENQNQRLMNLRSAERSVSFKAFHRHAEIN 130

  Fly   133 AWLQSLAQTNPGVVTLIEGGKTYQGRSILGVKITKGGETINGKAKPG---IFLEAGIHAREWIAP 194
            |:|..||...|..|::...||:|:.|.|..:.||      ||..|.|   :||:||||||||||.
  Fly   131 AYLDELAAAYPSRVSVQVAGKSYENRDIKTITIT------NGDGKTGKNVVFLDAGIHAREWIAH 189

  Fly   195 AAATFIINQLLTSEVENIKELAENYTWYVLPHANPDGYVYTHTTNRLWRKTRTPYGS-CFGADPN 258
            |.|.::|:||:.:...| .||.:::.|.:||..|||||.|:|||.|:|||||.|..| |:|.|.|
  Fly   190 AGALYVIHQLVENFAAN-SELLKDFDWVILPVVNPDGYEYSHTTTRMWRKTRKPISSACYGTDAN 253

  Fly   259 RNWGFHWNEVGASSSACSDTYAGPSAFSEIETLSLSKFIEGLKGKVQLYLSLHAYSQYLLYPYGH 323
            ||:.|||.||||||.:||||:.|.:||||.||..:...:..|.|:.:.||:||:|..|||||:|.
  Fly   254 RNFDFHWGEVGASSYSCSDTFKGETAFSEPETQLIRDILLSLTGRGKFYLTLHSYGNYLLYPWGW 318

  Fly   324 TSDLPDNVADFEKVFDASIAAVNKRYGTTYTGGNIYDAIYPAAGASVDWAYGTQDVRMAFCYELR 388
            ||.||.:..|.::|......|:....||.||.|:..:.:|.|||.|.|:|:|..:..::...||.
  Fly   319 TSALPSSWRDNDEVAQGGADAIKSATGTKYTVGSSTNVLYAAAGGSDDYAFGVANFPVSITMELP 383

  Fly   389 PSSTSYLTGFKLPAEQIVPASEELLDSIVAMATEV 423
            ...    |||.....||.....|....|.|||.:|
  Fly   384 AGG----TGFNPSTSQIEGFVSETWVGIKAMAQKV 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17633	NP_609310.2	MpaA	7..374	CDD:225421	145/374 (39%)
		Propep_M14	34..105	CDD:280416	17/71 (24%)
		M14_CP_A-B_like	125..423	CDD:199844	128/301 (43%)
CG8560	NP_001261516.1	Propep_M14	29..98	CDD:280416	17/69 (25%)
CG8560	NP_001261516.1	M14_CP_A-B_like	123..414	CDD:199844	128/301 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467010
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	239	1.000	Inparanoid score	I2114
Isobase	1	0.950	-	0	Normalized mean entropy	S1851
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	11	10.750