DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17633 and CG8562

DIOPT Version :9

Sequence 1:	NP_609310.2	Gene:	CG17633 / 34297	FlyBaseID:	FBgn0032144	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_648118.1	Gene:	CG8562 / 38828	FlyBaseID:	FBgn0035779	Length:	424	Species:	Drosophila melanogaster

Alignment Length:	434	Identity:	165/434 - (38%)
Similarity:	235/434 - (54%)	Gaps:	41/434 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LLAIVASASVSAERVRYDNYRMYKVNSENAKQLEVLKDLEGSSDSIMFLDGVHLVGADIQIIVAP 75
            ||.:...|::.|....|:.||:|:|....|.|.::|..|  |.....|:....|:|...::||:|
  Fly     7 LLVLFLGATLVAAEQDYEGYRIYEVIPSTADQADLLHQL--SLQGYDFISETRLLGHPSRVIVSP 69

  Fly    76 HKVPDFLEI--------------LGKSEIKYELQSRDVQKSLDEIDEKVAIKGRATTAYNWAQYY 126
            .::..|.::              ||.| |..|...|.:|:.|..|..    |||.:|    .:||
  Fly    70 AQLKHFQQLVEAEKMTLTLVNSNLGAS-IAEEFAQRQMQRLLAPITG----KGRLST----ERYY 125

  Fly   127 ELDDTYAWLQSLAQTNPGVVTLIEGGKTYQGRSILGVKITKGGETINGKA-KPGIFLEAGIHARE 190
            ..::...::..|||..|..|.:...|.:|:.|.:..:.||.|    :||| |..||::.|.||||
  Fly   126 THEEIINYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNG----DGKANKKVIFMDGGFHARE 186

  Fly   191 WIAPAAATFIINQLLTSEVENIKELAENYTWYVLPHANPDGYVYTHTTN--RLWRKTRTPY---- 249
            ||:|||..::|:||:....|| ..|.::|.|.:||..|.|||.:|.|..  |:|||||.||
  Fly   187 WISPAAVLYVIDQLVEQFEEN-AHLLKDYDWVILPLVNADGYEHTQTGTLARMWRKTRQPYTYAG 250

  Fly   250 GSCFGADPNRNWGFHWNEVGASSSACSDTYAGPSAFSEIETLSLSKFIEGLKGKVQLYLSLHAYS 314
            .:|:|||||||:.|||||.||||:.|:||||||:||||.||:::...:..|..:..:||:||:|.
  Fly   251 QTCYGADPNRNFDFHWNEEGASSNPCADTYAGPTAFSEPETITVRDLMHSLADRGIMYLTLHSYG 315

  Fly   315 QYLLYPYGHTSDLPDNVADFEKVFDASIAAVNKRYGTTYTGGNIYDAIYPAAGASVDWAYGTQDV 379
            .|||||:|.|||||:|..|.:.|......|:....||.||.|:..:.:|.|||||.|:.| ....
  Fly   316 NYLLYPWGWTSDLPENWEDLDAVARTGAEAIENATGTVYTYGSSTNVLYIAAGASDDYGY-YAGF 379

  Fly   380 RMAFCYELRPSSTSYLTGFKLPAEQIVPASEELLDSIVAMATEV 423
            .::...|| |.:.|  .||..|..:|.....|....|.|||.:|
  Fly   380 NVSITMEL-PGAGS--IGFNPPVTRIDEFVTETWIGIRAMAEKV 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17633	NP_609310.2	MpaA	7..374	CDD:225421	150/383 (39%)
		Propep_M14	34..105	CDD:280416	21/84 (25%)
		M14_CP_A-B_like	125..423	CDD:199844	130/304 (43%)
CG8562	NP_648118.1	Propep_M14	30..99	CDD:280416	17/71 (24%)
CG8562	NP_648118.1	M14_CP_A-B_like	124..420	CDD:199844	130/304 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467001
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1851
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	10	9.700