DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17633 and CG14820

DIOPT Version :9

Sequence 1:	NP_609310.2	Gene:	CG17633 / 34297	FlyBaseID:	FBgn0032144	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_648060.1	Gene:	CG14820 / 38754	FlyBaseID:	FBgn0035718	Length:	416	Species:	Drosophila melanogaster

Alignment Length:	429	Identity:	148/429 - (34%)
Similarity:	231/429 - (53%)	Gaps:	25/429 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LLFALLAIVA--SASVSAERVRYDNYRMYKVNSENAKQLEVLKDLEGSSDSIMFLDGVHLVGADI 69
            :|..:|.:|.  ..:.|.|:||||||::|.|..::.:|.::|...|.|.....:.:..|| |...
  Fly     1 MLLKILLVVGLFGLARSVEQVRYDNYKVYNVRIDDLEQFKLLHTQERSLKLSSWREARHL-GESS 64

  Fly    70 QIIVAPHKVPDFLEILGKSEIKYELQSRDVQKSLDEIDEKVAIKGRATTAYNWAQYYELDDTYAW 134
            .|::.|.....|..:|.|....|.|:..:||..:|....|..|     |:..|.|::.|::.|||
  Fly    65 DIMLPPEYQKTFESLLTKHNFTYNLKIDNVQTHIDAQRPKQRI-----TSMEWTQFHTLEEIYAW 124

  Fly   135 LQSLAQTNPGVVTLIEGGKTYQGRSILGVKIT-KGGETINGKAKPGIFLEAGIHAREWIAPAAAT 198
            |..:....|.:||....|.:|:||.|.||||: |.|       .|.:|:|:.|||||||..|..|
  Fly   125 LDVIEDRYPDIVTPFTIGNSYEGRPIRGVKISYKEG-------NPAVFIESNIHAREWITSATIT 182

  Fly   199 FIINQLLTSEVENIKELAENYTWYVLPHANPDGYVYTHTTNRLWRKTR---TPYGSCFGADPNRN 260
            :.|::||......::::|:|..||::|..|.||:.|:|...|||||:|   .|.|.|.|.|.|||
  Fly   183 YFIDELLVPRNPAVRDIAQNVDWYIIPVLNTDGFAYSHEVERLWRKSRLPSDPTGECIGTDLNRN 247

  Fly   261 WGFHWNEVGASSSACSDTYAGPSAFSEIETLSLSKFIEGL--KGKVQLYLSLHAYSQYLLYPYGH 323
            :.:.|...||.|..||..|||||..|:.|...|:.:|...  :|.:::|:|||:|.||:|.|:||
  Fly   248 FDYLWMLTGAESDPCSQLYAGPSPESDPEISQLTAYINNSIPEGTIKIYISLHSYGQYVLSPWGH 312

  Fly   324 TS-DLPDNVADFEKVFDASIAAVNKRYGTTYTGGNIYDAIYPAAGASVDWAYGTQDVRMAFCYEL 387
            |: :.|::......|......|:.:||||.:|.|:....:|..:|:..:|||..:::::.:..||
  Fly   313 TALEFPEHYPQMMHVAKGFSDALYRRYGTVFTYGSSATTLYEVSGSGKEWAYAVKNIKIHYTIEL 377

  Fly   388 RPSSTSYLTGFKLPAEQIVPASEELLDSIVAMATEVKSL 426
            |....   .||.||.|.|:|.:.|:.:..|.|....:.:
  Fly   378 RDKGE---LGFVLPPEDIIPVAREVTEGFVGMIAAAREI 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17633	NP_609310.2	MpaA	7..374	CDD:225421	133/375 (35%)
		Propep_M14	34..105	CDD:280416	17/70 (24%)
		M14_CP_A-B_like	125..423	CDD:199844	113/304 (37%)
CG14820	NP_648060.1	Propep_M14	31..100	CDD:280416	17/69 (25%)
CG14820	NP_648060.1	M14_CP_A-B_like	115..410	CDD:199844	113/304 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467030
Domainoid	1	1.000	224	1.000	Domainoid score	I1450
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	239	1.000	Inparanoid score	I2114
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm6559
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
	11	10.800