DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17633 and CG7025

DIOPT Version :9

Sequence 1:	NP_609310.2	Gene:	CG17633 / 34297	FlyBaseID:	FBgn0032144	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_609133.2	Gene:	CG7025 / 34042	FlyBaseID:	FBgn0031930	Length:	429	Species:	Drosophila melanogaster

Alignment Length:	435	Identity:	167/435 - (38%)
Similarity:	247/435 - (56%)	Gaps:	20/435 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSLNKC-LLFALLAIVASASVSA-ERVRYDNYRMYKVNSENAKQLEVLKDLEGSSDSIMFLDGVH 63
            |:||.. ::.||:.:...||... ||:|||||.:|||..|...|..:|:.|....::....   |
  Fly     1 MALNSLPIVLALVVLAQGASFGQDERLRYDNYSVYKVKFETQAQRSILRKLAEDRENFRLW---H 62

  Fly    64 LVGADIQIIVAPHKVPDFLEILGKSEIKYELQSRDVQKSLDEIDEKVAIKGRATTAYNWAQYYEL 128
            ....::.::::|....:....:.|:.:..||...:||:.:|. :|...:|......:.|.:|..|
  Fly    63 EAKDELHLMLSPGAFGELETEIQKTNVTAELFISNVQELIDS-EEAANLKASRDGTFGWTKYNSL 126

  Fly   129 DDTYAWLQSLAQTNPGVVTLIEGGKTYQGRSILGVKITKGGETINGKAKPGIFLEAGIHAREWIA 193
            .:.||||..:....|.:......|::|:||:|.|:||:....      .||:.:|:.|||||||.
  Fly   127 AEIYAWLDDILAAYPTITESFIVGQSYEGRTIRGIKISYKSN------NPGVLIESNIHAREWIT 185

  Fly   194 PAAATFIINQLLTSEVENIKELAENYTWYVLPHANPDGYVYTHTTNRLWRKTRTP--YGSCFGAD 256
            .|.||::||:.|||..|.:::||||:.||::|..|.||:||||..:|:|||||.|  ..||.|||
  Fly   186 SATATWLINEFLTSTDELVRDLAENHDWYIVPVLNVDGFVYTHEKDRMWRKTRQPSEISSCIGAD 250

  Fly   257 PNRNWGFHWNE-VGASSSACSDTYAGPSAFSEIETLSLSKFIEGLKGKVQLYLSLHAYSQYLLYP 320
            ||||:..||.| .||||:.|::.|.||..|||.|..::|:|:..:|.|:.:.|:.|:|||.||.|
  Fly   251 PNRNYDSHWMENEGASSNPCAEDYGGPKPFSEPEIQAMSEFVISIKDKINVLLAFHSYSQLLLSP 315

  Fly   321 YGHT-SDLPDNVADFEKVFDASIAAVNK-RYGTTYTGGNIYDAIYPAAGASVDWAYGTQDVRMAF 383
            |||| .:.|.|..|..:|..|...||.. .|||.|..|:....:|||:||::||||..|.|.:::
  Fly   316 YGHTKEEFPPNFDDMMEVAKAYGDAVESLPYGTVYRYGSAAGILYPASGATIDWAYNEQGVEISY 380

  Fly   384 CYELRPSSTSYLTGFKLPAEQIVPASEELLDSIVAMATEVKSLGY 428
            ..|.|.:..   .||.||...|:|.:||.|..|.|:..:.|.|||
  Fly   381 TIEFRDTGR---YGFILPPVHIIPNAEEALIGIAALLEKCKDLGY 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17633	NP_609310.2	MpaA	7..374	CDD:225421	143/372 (38%)
		Propep_M14	34..105	CDD:280416	13/70 (19%)
		M14_CP_A-B_like	125..423	CDD:199844	131/302 (43%)
CG7025	NP_609133.2	Propep_M14	36..103	CDD:280416	13/69 (19%)
CG7025	NP_609133.2	M14_CP_A-B_like	123..416	CDD:199844	131/301 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467036
Domainoid	1	1.000	224	1.000	Domainoid score	I1450
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	239	1.000	Inparanoid score	I2114
Isobase	1	0.950	-	0	Normalized mean entropy	S1851
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm6559
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
	13	12.780