DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17633 and cpa1

DIOPT Version :9

Sequence 1:	NP_609310.2	Gene:	CG17633 / 34297	FlyBaseID:	FBgn0032144	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_001018318.1	Gene:	cpa1 / 325886	ZFINID:	ZDB-GENE-050522-438	Length:	418	Species:	Danio rerio

Alignment Length:	437	Identity:	134/437 - (30%)
Similarity:	236/437 - (54%)	Gaps:	41/437 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LLAIVASASVSAERVRYDNYRMYKVNSENAKQLEVLKDLEGSSDSIMFLDGVHLVGADIQIIVAP 75
            ||.:.|.......:|.::..::.::|::||:|:.:||:|..:.          |:|.|..:..|.
Zfish     4 LLVLTALFVAVFGKVTFEGDQVLRINAKNAEQISLLKELTEAD----------LLGLDFWMNPAR 58

  Fly    76 HKVPDFLEI-----------LGKSEIKYELQSRDVQKSLDEIDEKVAIK----GRATTAYNWAQY 125
            ..:|..|.:           |..::|.|.:...:||..:|: ::...:|    .|:|..:.:..|
Zfish    59 ESLPVDLHVPFHSLQAVRAFLAYNQIPYHIMIENVQDLVDK-EQLQMLKYHGFPRSTDDFVYTTY 122

  Fly   126 YELDDTYAWLQSLAQTNPGVVTLIEGGKTYQGRSILGVKITKGGETINGKAKPGIFLEAGIHARE 190
            ::||....::..|...|..:|:.||.|::|:.|.:..:|.:.|..      :|||:::.|:|:||
Zfish   123 HDLDSINLFMDMLVAENQNMVSKIEIGQSYENRPLNVLKFSTGAN------RPGIWIDTGLHSRE 181

  Fly   191 WIAPAAATFIINQLLTSEVEN--IKELAENYTWYVLPHANPDGYVYTHTTNRLWRKTR--TPYGS 251
            ||..|:..:...:::|....:  :.::..:|..::...|||||..|||:.:|:|||||  .|..|
Zfish   182 WITHASGIWFAKKIVTDYGRDPVLTDILNSYDIFLEIVANPDGLAYTHSDDRMWRKTRKPNPGSS 246

  Fly   252 CFGADPNRNWGFHWNEVGASSSACSDTYAGPSAFSEIETLSLSKFIEGLKGKVQLYLSLHAYSQY 316
            |.|.||||||...:...|:||:.||.||.|||..||.|..::.:|::. .|.::.:||:|:|||.
Zfish   247 CVGVDPNRNWETGFGGPGSSSNPCSQTYHGPSIHSEPEVKAIVEFVKS-HGNLKAFLSIHSYSQM 310

  Fly   317 LLYPYGHTSDLPDNVADFEKVFDASIAAVNKRYGTTYTGGNIYDAIYPAAGASVDWAYGTQDVRM 381
            ||||||:|.....:.|:..::...:.:.:...|.|.||.|:|...||.|.|.:.|||| .|.::.
Zfish   311 LLYPYGYTQTAAKDQAELHELARKATSELQSLYNTAYTYGSIITTIYQADGVTTDWAY-EQGIKY 374

  Fly   382 AFCYELRPSSTSYLTGFKLPAEQIVPASEELLDSIVAMATEVKSLGY 428
            ::.:|||.:..   .||.|||:||:|.:||...:::.:...:|:..|
Zfish   375 SYTFELRDTGR---YGFILPADQILPTAEETWLALMVIMEHIKNNPY 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17633	NP_609310.2	MpaA	7..374	CDD:225421	116/381 (30%)
		Propep_M14	34..105	CDD:280416	18/81 (22%)
		M14_CP_A-B_like	125..423	CDD:199844	106/301 (35%)
cpa1	NP_001018318.1	Propep_M14	27..99	CDD:280416	18/81 (22%)
cpa1	NP_001018318.1	Peptidase_M14_like	117..416	CDD:299699	107/309 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593529
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55609
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm6559
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.750