DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17633 and cpb1

DIOPT Version :9

Sequence 1:	NP_609310.2	Gene:	CG17633 / 34297	FlyBaseID:	FBgn0032144	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_001315354.1	Gene:	cpb1 / 322412	ZFINID:	ZDB-GENE-030131-1132	Length:	416	Species:	Danio rerio

Alignment Length:	435	Identity:	147/435 - (33%)
Similarity:	235/435 - (54%)	Gaps:	45/435 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LFALLAIVASASVSAERVRYDNYRMYKVNSENAKQLEVLKDL----------EGSSDSI---MFL 59
            ||.||.:||.|  ..|.:.:...::.::...|.:.:.::::|          ..|:|.:   |.:
Zfish     3 LFLLLGLVAVA--LCEPITFVGDKVLQLKPINDEHVTIIRELGEKIKLDFWKPRSADLVSIDMTV 65

  Fly    60 DGVHLVGADIQIIVAPHKVPDFLEILGKSEIKYELQSRDVQKSL-DEIDEKVAIKGRATTAYN-W 122
            | :|:..|.:.::..         ||.:|:::.::...::|::: .::|.:...||...|.|| |
Zfish    66 D-IHVPAAQLAMVST---------ILQQSDMEVKVMIDNLQEAVKGQMDNRSPTKGHDYTKYNSW 120

  Fly   123 AQYYELDDTYAWLQSLAQTNPGVVTLIEGGKTYQGRSILGVKITKGGETINGKAKPGIFLEAGIH 187
            |   .::|   |..|::..||.:::....|.||:||::..:||.|.    .|..||.:|::.|.|
Zfish   121 A---TIND---WAISISSANPDLISRQSIGNTYEGRTMHLLKIGKN----TGSNKPAVFMDCGFH 175

  Fly   188 AREWIAPAAATFIINQLLTS--EVENIKELAENYTWYVLPHANPDGYVYTHTTNRLWRKTRTPY- 249
            |||||..|...:.:|:.:::  ...::..|.:...::|||..|.|||.||...:|:|||||:..
Zfish   176 AREWITHAFCQWFVNEAVSTYGSDPDMTNLLDRMDFFVLPVFNIDGYEYTWNRDRMWRKTRSKNS 240

  Fly   250 -GSCFGADPNRNWGFHWNEVGASSSACSDTYAGPSAFSEIETLSLSKFIEGLKGKVQLYLSLHAY 313
             .||.|.|||||:...|..|||||:.|||||.|.|..||||:.:|:.||...|..::.||::|:|
Zfish   241 GSSCIGTDPNRNFNAGWCTVGASSNPCSDTYCGSSPESEIESKNLANFIRTNKSVIKAYLTVHSY 305

  Fly   314 SQYLLYPYGHTSDLPDNVADFEKVFDASIAAVNKRYGTTYTGGNIYDAIYPAAGASVDWAYGTQD 378
            ||.||:||.:..||..:.::...|...:|||:...|||.||.|.....||||||.|.||||.. .
Zfish   306 SQLLLFPYSYKYDLAAHHSELMSVSQGAIAALRSLYGTKYTSGPGAATIYPAAGGSDDWAYDL-G 369

  Fly   379 VRMAFCYELRPSSTSYLTGFKLPAEQIVPASEELLDSIVAMATEV 423
            |:.::.:|||....   .||.||..||.|..||.:.::..:|..|
Zfish   370 VKYSYTFELRDEGR---YGFLLPESQIKPTCEETMLAVKYIANHV 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17633	NP_609310.2	MpaA	7..374	CDD:225421	130/384 (34%)
		Propep_M14	34..105	CDD:280416	12/84 (14%)
		M14_CP_A-B_like	125..423	CDD:199844	118/301 (39%)
cpb1	NP_001315354.1	M14_CPB	112..412	CDD:199852	124/314 (39%)
cpb1	NP_001315354.1	Propep_M14	27..99	CDD:280416	12/81 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593433
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm6559
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.680