DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17633 and CG3108

DIOPT Version :9

Sequence 1:	NP_609310.2	Gene:	CG17633 / 34297	FlyBaseID:	FBgn0032144	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster

Alignment Length:	394	Identity:	136/394 - (34%)
Similarity:	217/394 - (55%)	Gaps:	35/394 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RYDNYRMYKVNSENAKQLEVLKDLEGSSDSIMFLDGVHLVGADIQIIVAPHKVPDFLEILGKSE- 89
            |||..:::::..:..|...:..:|:...|..::.:    |..::..::.|       ::|..:|
  Fly   722 RYDGAQVWRIVVQTDKDKRMADELQSKYDGQLWKE----VKQEVDYLLKP-------QVLAAAER 775

  Fly    90 -IKYELQSR-----DVQKSLDEID---EKVA-IKGRATTAYNWAQYYELDDTYAWLQSLAQTNPG 144
             |:....||     ::|:.:::.:   ||:| ::.|......|..|:.|:|.:.::..:|:|.|.
  Fly   776 HIRAANLSRIVLIDNLQRVIEKENPPAEKIAELQNRKGHRLTWQAYHRLEDIHGFIDYMAKTYPD 840

  Fly   145 VVTLIEGGKTYQGRSILGVKITKGGETINGKAK-PGIFLEAGIHAREWIAPAAATFIINQLLTSE 208
            :.:....|.:.:.|.:..:||:      ||.|: |||:::.|:||||||:||..|:|.|||:..
  Fly   841 ICSTEIIGYSVEKRPLKILKIS------NGNARNPGIWIDGGMHAREWISPATVTYIANQLVEG- 898

  Fly   209 VENIKELAENYTWYVLPHANPDGYVYTHTTNRLWRKTRTPYG-SCFGADPNRNWGFHWNEVGASS 272
            .|::.|...:..||:.|.||||||.|:|||:|||||....:| .|.|.|.|||:|:.|...|.|:
  Fly   899 WEDLPEHMRSINWYIHPVANPDGYEYSHTTDRLWRKNMRAHGRQCPGVDLNRNFGYKWGGKGTSA 963

  Fly   273 SACSDTYAGPSAFSEIETLSLSKFIEGL-KGKVQLYLSLHAYSQYLLYPYGHTSDLPDNVADFEK 336
            |.||.||.|..||||.||..:||||.|. :...|.|||.|:|.||:|||:|:...|..:.||.::
  Fly   964 SPCSQTYRGSKAFSEPETFYISKFISGFPRETFQAYLSFHSYGQYILYPWGYDYQLTQDRADLDR 1028

  Fly   337 VFDASIAAVNKRYGTTYTGGNIYDAIYPAAGASVDWAYGTQDVRMAFCYELRPSSTSYLTGFKLP 401
            |...:..::.|..|..||.|:....:|||||.|.|||.|...::.|:..|:..:..   .||.||
  Fly  1029 VARQAGTSITKSTGVKYTVGSSATTLYPAAGGSDDWAKGIAGIKYAYTIEMGDTGR---YGFVLP 1090

  Fly   402 AEQI 405
            |..|
  Fly  1091 ARFI 1094

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17633	NP_609310.2	MpaA	7..374	CDD:225421	126/361 (35%)
		Propep_M14	34..105	CDD:280416	11/77 (14%)
		M14_CP_A-B_like	125..423	CDD:199844	117/284 (41%)
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416	11/77 (14%)
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844	117/284 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466962
Domainoid	1	1.000	225	1.000	Domainoid score	I2535
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
	11	10.780