DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17633 and CG3097

DIOPT Version :9

Sequence 1:	NP_609310.2	Gene:	CG17633 / 34297	FlyBaseID:	FBgn0032144	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_572259.1	Gene:	CG3097 / 31503	FlyBaseID:	FBgn0029804	Length:	445	Species:	Drosophila melanogaster

Alignment Length:	459	Identity:	133/459 - (28%)
Similarity:	229/459 - (49%)	Gaps:	58/459 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KCLLFALLAIVASASVS-------------AERV--RYDN---YRMYKVNSENAKQLEVLKDLEG 51
            |.:|..||.:||:.:.|             |..:  |||.   :|:|.::....|::.|.:.||.
  Fly     4 KTMLLQLLLLVAAVAASLANELPSNLTLLDANEIPQRYDEAQLWRIYNISEAMQKRVPVGQMLEQ 68

  Fly    52 S------SDSIMFLDGVHLVGADIQIIVAPHKVPDFLEILGKSEIKYELQSRDVQKSLDE----- 105
            .      .::..|||          |.:|..::......|....:..::.|.::|..:||
  Fly    69 KFGGNIWKENSKFLD----------ISIARDQLKAARSFLSAHRLDPQILSHNIQSMIDEELLEG 123

  Fly   106 IDEKVAIKGRAT-----TAYNWAQYYELDDTYAWLQSLAQTNPGVVTLIEGGKTYQGRSILGVKI 165
            |.......||.|     ::.:|..|::|:..|::::.:....|.:|.|...|:|.:||.:..::|
  Fly   124 IQSSSFGHGRRTKKAARSSMHWKDYHDLETIYSFMREIRTKFPNIVRLYTIGQTAEGRDLKVLRI 188

  Fly   166 TKGGETINGKAKPGIFLEAGIHAREWIAPAAATFIINQLLTSEVENIKELAENYTWYVLPHANPD 230
            ::     |.:....::::.||||||||:||..|||:.||: |:.||........|||::|..|||
  Fly   189 SE-----NPRENKKVWIDGGIHAREWISPATVTFILYQLM-SDWENQPAHIRGLTWYIMPVMNPD 247

  Fly   231 GYVYTHTTNRLWRKTRTP--YGSCFGADPNRNWGFHWNEVGASSSACSDTYAGPSAFSEIETLSL 293
            ||.|:.||||||||.|:|  ...|.|.|.|||:...||..|:|::.|||||.|.:..||.||.::
  Fly   248 GYEYSRTTNRLWRKNRSPSRRAQCSGVDLNRNFDIGWNGYGSSTNPCSDTYRGSAPASERETRAV 312

  Fly   294 SKFIEGLKGKVQLYLSLHAYSQYLLYPYGHTSDLPDNVADFEKVFDASIAAVNKRYGTTYTGGNI 358
            ::|:...|..::.||:.|:|.|.::||:.:.:....:.:..::|...:...:.::.||:|.....
  Fly   313 AEFLAKRKYNLESYLTFHSYGQMIVYPWAYKAVKVKDASVLQRVSSLAAERILQKTGTSYRAAVT 377

  Fly   359 YDAIYPAAGASVDWAYGTQDVRMAFCYELRPSSTSYLTGFKLPAEQIVPASEELLDSIVAMATEV 423
            ::.:..|.|.|.||:.....|:..:..|||... :|  ||.||...|   .:..|:....:.|..
  Fly   378 HEVLGIAGGGSDDWSRAALGVKYVYTIELRDRG-AY--GFVLPPRFI---KDTALEGWTVVETVA 436

  Fly   424 KSLG 427
            :::|
  Fly   437 QAIG 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17633	NP_609310.2	MpaA	7..374	CDD:225421	119/402 (30%)
		Propep_M14	34..105	CDD:280416	12/76 (16%)
		M14_CP_A-B_like	125..423	CDD:199844	100/299 (33%)
CG3097	NP_572259.1	Propep_M14	64..118	CDD:280416	10/63 (16%)
CG3097	NP_572259.1	M14_CP_A-B_like	148..439	CDD:199844	100/302 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466965
Domainoid	1	1.000	225	1.000	Domainoid score	I2535
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
	9	8.850