DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17633 and Agbl2

DIOPT Version :9

Sequence 1:	NP_609310.2	Gene:	CG17633 / 34297	FlyBaseID:	FBgn0032144	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_848870.2	Gene:	Agbl2 / 271813	MGIID:	2443254	Length:	862	Species:	Mus musculus

Alignment Length:	348	Identity:	73/348 - (20%)
Similarity:	119/348 - (34%)	Gaps:	121/348 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 YELDDTYAWLQSLAQTNPGVVTLIEGG--------KTYQGRSILGVKITKGGET-INGKAKPGIF 181
            |...|...:|.|:| .||     |:..        ::..|.::..:.||....| ....||..:.
Mouse   361 YTYTDLQCYLLSVA-NNP-----IQSQFCKLRALCRSLAGNTVYLLTITNPSRTPQEAAAKKAVV 419

  Fly   182 LEAGIHARE----WIAPAAATFIINQLLTSEVENIKELAENYTWYVLPHANPDGYVYTHTTNRLW 242
            |.|.:|..|    ||......||:     |...:.:.|.:.:.:.|:|..||||.:..:     :
Mouse   420 LSARVHPGESNSSWIMNGFLDFIL-----SNSPDAQLLRDIFVFKVIPMLNPDGVIVGN-----Y 474

  Fly   243 RKTRTPYGSCFGADPNRNWGFHWNEVGASSSACSDTYAGPSAFSEIETLSLSKFIEGLKGKVQLY 307
            |      .|..|.|.||    |:..|...|..|. .|.         ...:.:.:|  :.:|.||
Mouse   475 R------CSLAGRDLNR----HYKTVLKDSFPCI-WYT---------KNMIKRLLE--EREVLLY 517

  Fly   308 LSLHAYSQ----YL---------------LYPYGHTSDLPDNVADFEKVFDASIAAVNK-RYGT- 351
            ...|.:|:    :|               ::|...:.:.||..:     ||:....|.| :.||
Mouse   518 CDFHGHSRKNNIFLYGCHSNNRKHWLHERVFPLMLSKNAPDKFS-----FDSCNFKVQKCKEGTG 577

  Fly   352 -----------TYT-----GGNIYDAIYPAAGASVDWAYGTQDVR----------MAFCYELRPS 390
                       :||     ||:       ..|:..|..:..:|::          :.||   .|.
Mouse   578 RVVMWRMGIINSYTMESTFGGS-------TLGSKRDTHFTIEDLKSLGYHVCDTLLDFC---DPD 632

  Fly   391 STSYLTGFKLPAEQIVPASEELL 413
            .|.|        .|.:...:|||
Mouse   633 QTKY--------TQCLQELKELL 647

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17633	NP_609310.2	MpaA	7..374	CDD:225421	63/297 (21%)
		Propep_M14	34..105	CDD:280416
		M14_CP_A-B_like	125..423	CDD:199844	73/348 (21%)
Agbl2	NP_848870.2	Pepdidase_M14_N	231..358	CDD:375499
		M14_AGBL2-3_like	379..629	CDD:349478	56/293 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	669..692
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	704..728
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	750..836
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900