DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17633 and SPBC337.07c

DIOPT Version :9

Sequence 1:	NP_609310.2	Gene:	CG17633 / 34297	FlyBaseID:	FBgn0032144	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_595408.1	Gene:	SPBC337.07c / 2541067	PomBaseID:	SPBC337.07c	Length:	497	Species:	Schizosaccharomyces pombe

Alignment Length:	504	Identity:	133/504 - (26%)
Similarity:	216/504 - (42%)	Gaps:	105/504 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSLNKCLLFALLAIVASASVSAERVRYDNYRMYKVNSENAKQLEVL--KDLEGSSDSIMFLDGVH 63
            |:.||.|...:..::||..|         :.::....:::::|.|.  .|:.....|.:..:|..
pombe     1 MAYNKSLKSLVFILLASQIV---------FVLFLCYGKSSRELGVKWNSDIRSWMTSYVGFNGET 56

  Fly    64 LVGADIQIIVAPHKVPDFLEIL----------GKSEIKYELQSRDV---QKSLDEID-------- 107
            ...::.|:|.| .|:||:.|.:          ..|:|..:.||:::   ..:.|.:|
pombe    57 AAISEEQLIWA-EKIPDYNEEIVVRLHLEEENNLSDILQKAQSQNLDIWDYNFDHVDLRLKEENF 120

  Fly   108 --------EKVAIKGRATTAYN-------------------------------------WAQYYE 127
                    ..:.|.....|.:.                                     :..|..
pombe   121 DFWKSQYRSDILINNLTETLFESIVPDTTNSPFSTEAFLQAVENGHLNHEMFTSFTDIFFKSYQN 185

  Fly   128 LDDTYAWLQSLAQTNPGVVTLIEGGKTYQGRSILGVKI-----TKGGETINGKAKPGIFLEAGIH 187
            |:...:||:.:|.....:..|:..|.|.:||:|||:|:     :..||.|..|..  |.::.|.|
pombe   186 LESINSWLRLMASLYKDLSELVPVGITAEGRTILGLKLNGRHPSDNGEKIRNKKV--IIIQGGSH 248

  Fly   188 AREWIAPAAATFIINQLLT--SEVENIKELAENYTWYVLPHANPDGYVYTHTTNRLWRKTRTPYG 250
            |||||...:..:...|||.  ....::::|.:.:.|..:|..|.|||.||.:.:|||.|.|.|..
pombe   249 AREWIGIPSVCYAAWQLLAKYDSDGHVRKLLDKFEWIFIPVLNVDGYEYTWSNDRLWSKNRQPLN 313

  Fly   251 S--CFGADPNRNWGFHWNEVGASSSACSDTYAGPSAFSEIETLSLSKFI-EGL---KGKVQLYLS 309
            :  |||.:.:.||.|.:|   .:...||:.|.|.|.|...||::|...| |.|   :.||..:|.
pombe   314 NSECFGINLDANWAFGFN---GNIDPCSNEYGGLSPFQANETMALFNLITESLSQEQKKVVGFLD 375

  Fly   310 LHAYSQYLLYPYGHTSDL-PDNVADFEKV---FDASIAAVNKRYGTTYTGGNIYDAIYP--AAGA 368
            :|:|||.:|:||.:|.|| |.:..:||::   ....:..||.||.|.......||..:.  ..|.
pombe   376 VHSYSQSVLWPYAYTCDLFPPDTENFEELAIGLVKELHRVNSRYYTYQQACIPYDGFHKHYLPGT 440

  Fly   369 SVDWAYGTQDVRMAFCYELRPSSTSYLTGFKLPAEQIVPASEELLDSIV 417
            ::||.|...||...|...||... .|  |:.|||:||||.::|....|:
pombe   441 AIDWVYFAADVAWPFNIRLRDMG-DY--GYLLPAKQIVPTAKEFFAMIL 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17633	NP_609310.2	MpaA	7..374	CDD:225421	113/453 (25%)
		Propep_M14	34..105	CDD:280416	16/85 (19%)
		M14_CP_A-B_like	125..423	CDD:199844	106/312 (34%)
SPBC337.07c	NP_595408.1	MpaA	42..479	CDD:225421	121/445 (27%)
SPBC337.07c	NP_595408.1	M14_CP_A-B_like_1	180..492	CDD:199869	106/315 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
TreeFam	0	0.000	Not matched by this tool.
	9	8.840