DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17633 and AGTPBP1

DIOPT Version :9

Sequence 1:	NP_609310.2	Gene:	CG17633 / 34297	FlyBaseID:	FBgn0032144	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_001273644.1	Gene:	AGTPBP1 / 23287	HGNCID:	17258	Length:	1278	Species:	Homo sapiens

Alignment Length:	251	Identity:	57/251 - (22%)
Similarity:	94/251 - (37%)	Gaps:	66/251 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 YELDDTYAWLQSLAQT-----NPGVV-----TLIEGGKTYQGRSILGVKITKGGET------ING 174
            |....||:.||...|.     ||..:     .|.|   |..|.|...|.||...|:      .:.
Human   898 YHYPYTYSTLQMHLQKLESAHNPQQIYFRKDVLCE---TLSGNSCPLVTITAMPESNYYEHICHF 959

  Fly   175 KAKPGIFLEAGIHARE----WIAPAAATFIINQLLTSEVENIKELAENYTWYVLPHANPDGYVYT 235
            :.:|.:||.|.:|..|    |:......::::...|::     .|.|:|.:.::|..||||.:
Human   960 RNRPYVFLSARVHPGETNASWVMKGTLEYLMSNNPTAQ-----SLRESYIFKIVPMLNPDGVI-- 1017

  Fly   236 HTTNRLWRKTRTPYGSCFGADPNRNWGFHWNEVGASSSACSDTYAGPSAFSEIETLSLSKFIEGL 300
            :..:|.         |..|.|.||.|          .|...|.:  |:.:   ....|.:::..:
Human  1018 NGNHRC---------SLSGEDLNRQW----------QSPSPDLH--PTIY---HAKGLLQYLAAV 1058

  Fly   301 KGKVQLYLSLHAYSQYL-LYPYG--------HTSDLPDNVADFEKVFDASIAAVNK 347
            |....:|...|.:|:.. ::.||        ||:   ||....:.|.|.....:.|
Human  1059 KRLPLVYCDYHGHSRKKNVFMYGCSIKETVWHTN---DNATSCDVVEDTGYRTLPK 1111

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17633	NP_609310.2	MpaA	7..374	CDD:225421	57/251 (23%)
		Propep_M14	34..105	CDD:280416
		M14_CP_A-B_like	125..423	CDD:199844	57/251 (23%)
AGTPBP1	NP_001273644.1	M14_Nna1	911..1188	CDD:133116	52/238 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900