Protein Alignment CG17633 and CPB2

DIOPT Version :10

• Sequence 1: NP_609310.2
• Gene: CG17633 / 34297
• FlyBaseID: FBgn0032144
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_001863.3
• Gene: CPB2 / 1361
• HGNCID: 2300
• Length: 423
• Species: Homo sapiens
• Alignment Length: 405
• Identity: 121/405 - (29%)
• Similarity: 213/405 - (52%)
• Gaps: 42/405 - (10%)

  Fly    40 AKQLEVLKDLEGSSDSIMFLDGVHLVGADIQIIVAPHKVPDFLEILGKSEIKYELQSRDVQKSL- 103
            ::|::||::|..:.:.:::    ..|.||  :||...:|..|:.......:|..|....:..|:
Human    36 SRQVQVLQNLTTTYEIVLW----QPVTAD--LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVL 94

  Fly   104 -----DEIDEKVA---IKGRATTAYNWAQYYELDDTYAWLQSLAQTNPGVVTLIEGGKTYQGRSI 160
                 |.|.::::   :..||:.:| :.||:.|::.|:|::.:.:.:|.::|.|..|.:::...:
Human    95 LADVEDLIQQQISNDTVSPRASASY-YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPL 158

  Fly   161 LGVKITKGGETINGK---AKPGIFLEAGIHAREWIAPAAATFIINQL-----LTSEVENIKELAE 217
            ..:|       ::||   ||..|:::.||||||||:||...:.|..:     :..:..|:..|.:
Human   159 YVLK-------VSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVD 216

  Fly   218 NYTWYVLPHANPDGYVYTHTTNRLWRKTRTPYGS--CFGADPNRNWGF-HWNEVGASSSACSDTY 279
               :||:|..|.|||.|:...||:|||.|:.|.:  |.|.|.|||:.. ||.|.|||||:||:||
Human   217 ---FYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETY 278

  Fly   280 AGPSAFSEIETLSLSKFIEGLKGKVQLYLSLHAYSQYLLYPYGHTSDLPDNVADFEKVFDASIAA 344
            .|....||.|..:::.|:.....:::.|:|:|:|||::::||.:|.....:..:...|...::.|
Human   279 CGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRA 343

  Fly   345 VNK-RYGTTYTGGNIYDAIYPAAGASVDWAYGTQDVRMAFCYELRPSSTSYLTGFKLPAEQIVPA 408
            :.| ...|.||.|:..:.:|.|.|...||.|.. .::.:|..|||.:.|   .||.||...|.|.
Human   344 IEKISKNTRYTHGHGSETLYLAPGGGDDWIYDL-GIKYSFTIELRDTGT---YGFLLPERYIKPT 404

  Fly   409 SEELLDSIVAMATEV 423
            ..|...::..:|..|
Human   405 CREAFAAVSKIAWHV 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17633	NP_609310.2	Propep_M14	33..105	CDD:460505	14/70 (20%)
		Zn_pept	125..407	CDD:214748	97/293 (33%)
CPB2	NP_001863.3	Propep_M14	33..105	CDD:460505	16/74 (22%)
		M14_CPB2	119..420	CDD:349465	103/316 (33%)