Protein Alignment CG17633 and CPA3

DIOPT Version :10

• Sequence 1: NP_609310.2
• Gene: CG17633 / 34297
• FlyBaseID: FBgn0032144
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_001861.2
• Gene: CPA3 / 1359
• HGNCID: 2298
• Length: 417
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 132/422 - (31%)
• Similarity: 224/422 - (53%)
• Gaps: 29/422 - (6%)

  Fly     7 LLFALLAIVASASVSAERVRYDNYRMYKVNSENAKQLEVLKDLEGSSDSIMFLDG-VHLVGADIQ 70
            |:...|||..        ||:|..::::|..::.||.:::|||..:::...:..| .|.|.|::.
Human     9 LIATTLAIAP--------VRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAANMM 65

  Fly    71 I--IVAPHKVPDFLEILGKSEIKYELQSRDVQKSLD-EIDEKVAIKGRATTAYNWAQYYELDDTY 132
            :  .|:..:.......|.::::.||:...|:|:.:: :.|.|..|.||    :::|:|...:...
Human    66 VDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGR----HSYAKYNNWEKIV 126

  Fly   133 AWLQSLAQTNPGVVTLIEGGKTYQGRSILGVKITKGGETINGKAKPGIFLEAGIHAREWIAPAAA 197
            ||.:.:....|.:|:.|:.|.|.:...:..:||   ||  ..:.:..||.:.|||||||::||..
Human   127 AWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKI---GE--KNERRKAIFTDCGIHAREWVSPAFC 186

  Fly   198 TFIINQLLTSEVEN--IKELAENYTWYVLPHANPDGYVYTHTTNRLWRKTRT--PYGSCFGADPN 258
            .:.:.|...:...|  :.:|.:...:|:||..|.|||:::.|.||:|||.|:  ....|.|.|.|
Human   187 QWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCIGTDLN 251

  Fly   259 RNWGFHWNEVGASSSACSDTYAGPSAFSEIETLSLSKFIEGLKGKVQLYLSLHAYSQYLLYPYGH 323
            ||:...||.:..::..|:|.|.|.:..||.||.:::.||.....::::|::.|:|||.||:|||:
Human   252 RNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSYSQMLLFPYGY 316

  Fly   324 TSDLPDNVADFEKVFDASIAAVNKRYGTTYTGGNIYDAIYPAAGASVDWAYGTQDVRMAFCYELR 388
            ||.||.|..|..||.......::.||.|.|..|.|...|||.:|:|:||||.. .::..|.:|||
Human   317 TSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSLDWAYDL-GIKHTFAFELR 380

  Fly   389 PSSTSYLTGFKLPAEQIVPASEELLDSIVAMA 420
            ....   .||.||..:|.|...|.:.::..:|
Human   381 DKGK---FGFLLPESRIKPTCRETMLAVKFIA 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17633	NP_609310.2	Propep_M14	33..105	CDD:460505	16/75 (21%)
		Zn_pept	125..407	CDD:214748	100/285 (35%)
CPA3	NP_001861.2	Propep_M14	27..103	CDD:460505	16/75 (21%)
		M14_CPB	114..413	CDD:349443	104/305 (34%)