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Protein Alignment CG17633 and CPA2

DIOPT Version :9

Sequence 1:	NP_609310.2	Gene:	CG17633 / 34297	FlyBaseID:	FBgn0032144	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_001860.2	Gene:	CPA2 / 1358	HGNCID:	2297	Length:	419	Species:	Homo sapiens

Alignment Length:	408	Identity:	139/408 - (34%)
Similarity:	226/408 - (55%)	Gaps:	24/408 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 RMYKVNSENAKQLEVLKDLEGSSD-SIMFLDGVHLVG--ADIQI-IVAPHKVPDFLEILGKSEIK 91
            ::.::...|.:|::.|..||.... .:.|.......|  |.::: .|....|..|||..|   |.
Human    26 QVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVKVFLESQG---IA 87

  Fly    92 YELQSRDVQKSLDEIDEKVAIKGRATTA--YNWAQYYELDDTYAWLQSLAQTNPGVVTLIEGGKT 154
            |.:...|||..||:.:|::....|...:  :|:..|:.|::....:.:|...:||:|:.:..|.:
Human    88 YSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSS 152

  Fly   155 YQGRSILGVKITKGGETINGKAKPGIFLEAGIHAREWIAPAAATFIINQLLT--SEVENIKELAE 217
            ::.|.:..:|.:.||:      ||.|:|:||||||||:..|.|.:..|::::  .:..:|..:.:
Human   153 FENRPMNVLKFSTGGD------KPAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILD 211

  Fly   218 NYTWYVLPHANPDGYVYTHTTNRLWRKTRTPY-GS-CFGADPNRNWGFHWNEVGASSSACSDTYA 280
            ....::||..||||||::.|.||:|||||:.. || |.|.||||||...:...||||:.|||:|.
Human   212 ALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYH 276

  Fly   281 GPSAFSEIETLSLSKFIEGLKGKVQLYLSLHAYSQYLLYPYGHTSDLPDNVADFEKVFDASIAAV 345
            ||||.||:|..|:..||:. .|||:.:::||:|||.|::|||:.....|:..:..:|...:..::
Human   277 GPSANSEVEVKSIVDFIKS-HGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSL 340

  Fly   346 NKRYGTTYTGGNIYDAIYPAAGASVDWAYGTQDVRMAFCYELRPSSTSYLTGFKLPAEQIVPASE 410
            ...:||.|..|.|...||.|:|.|:||:| ...::.:|.:|||.:..   .||.|||.||:|.:|
Human   341 RSLHGTKYKVGPICSVIYQASGGSIDWSY-DYGIKYSFAFELRDTGR---YGFLLPARQILPTAE 401

  Fly   411 ELLDSIVAMATEVKSLGY 428
            |....:.|:...|:...|
Human   402 ETWLGLKAIMEHVRDHPY 419

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.