DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17633 and cpo.2

DIOPT Version :9

Sequence 1:	NP_609310.2	Gene:	CG17633 / 34297	FlyBaseID:	FBgn0032144	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	XP_002937157.1	Gene:	cpo.2 / 100487462	XenbaseID:	XB-GENE-22169695	Length:	454	Species:	Xenopus tropicalis

Alignment Length:	411	Identity:	124/411 - (30%)
Similarity:	219/411 - (53%)	Gaps:	32/411 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 VRYDNYRMYKVNSENAKQLEVLKDLEGSSDSIMFL------DGVHLVGADIQIIVAPHKVPDFLE 83
            |:|:...::|:..|.::..:.|:.|  :::.::.|      :.:| .|:||.:.:....:....:
Frog    23 VQYNGDNVFKITPETSEHAQYLQTL--ANEWLLDLWRPQTVEQIH-EGSDIHVQIPFAYMEQMKQ 84

  Fly    84 ILGKSEIKYELQSRDVQKSLDEID------EKVAIKGRATTAYNWAQYYELDDTYAWLQSLAQTN 142
            .|.:..|.||:...||||.:|...      :|.:::.     |::.:|:.:|:.|.|:..:.:.:
Frog    85 KLLQHSIPYEVLINDVQKLIDSNTVSAPKIQKASLEN-----YDYTKYHPMDEIYNWMDLMKEKH 144

  Fly   143 PGVVTLIEGGKTYQGRSILGVKITKGGETINGKAKPGIFLEAGIHAREWIAPAAATFIINQLLTS 207
            ..:|:....|.||:.|.:..:||....:    |.|...|::.|.||||||:.|...:.:|::::.
Frog   145 SEIVSQHYIGCTYELRPMYYLKIGWPSD----KQKKIFFIDCGFHAREWISVAFCQWFVNEIVSH 205

  Fly   208 EVEN--IKELAENYTWYVLPHANPDGYVYTHTTNRLWRKTRTPY--GSCFGADPNRNWGFHWNEV 268
            ...:  :..:.:...:||||..|.||||||.||||||||.|:|:  |:|:|.|.|||:...|..:
Frog   206 YKTDAILANVLKQVDFYVLPVMNIDGYVYTWTTNRLWRKNRSPHENGTCYGVDLNRNFDSQWCSI 270

  Fly   269 GASSSACSDTYAGPSAFSEIETLSLSKFIEGLKGKVQLYLSLHAYSQYLLYPYGHTSDLPDNVAD 333
            |||....|:|:.||.|.||.||.:||..||..|..:..||::|:|.|.:|.|||:..|...|..:
Frog   271 GASRDCNSNTFCGPEAASEPETKALSGLIEKTKSDILCYLTIHSYGQMILLPYGYKKDPSPNHDE 335

  Fly   334 FEKVFDASIAAVNKRYGTTYTGGNIYDAIYPAAGASVDWAYGTQDVRMAFCYELRPSSTSYLTGF 398
            ...|...::|.:.:::...|...:....:|..:|:|.||.. ...:::::..|||.:.|   .||
Frog   336 MMLVAKNAVAKMKEKHNNEYEYESSAVILYYDSGSSGDWTV-ELGIQLSYTLELRDNGT---YGF 396

  Fly   399 KLPAEQIVPASEELLDSIVAM 419
            .||.:||.|..||...::::|
Frog   397 VLPPDQIKPTCEETTTAVMSM 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17633	NP_609310.2	MpaA	7..374	CDD:225421	110/364 (30%)
		Propep_M14	34..105	CDD:280416	17/76 (22%)
		M14_CP_A-B_like	125..423	CDD:199844	102/299 (34%)
cpo.2	XP_002937157.1	Propep_M14	36..105	CDD:366995	16/71 (23%)
cpo.2	XP_002937157.1	M14_CPO	124..421	CDD:349466	102/302 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	240	1.000	Domainoid score	I2216
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.950