DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17633 and cpo

DIOPT Version :9

Sequence 1:	NP_609310.2	Gene:	CG17633 / 34297	FlyBaseID:	FBgn0032144	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_001139101.1	Gene:	cpo / 100005630	ZFINID:	ZDB-GENE-070619-6	Length:	363	Species:	Danio rerio

Alignment Length:	314	Identity:	106/314 - (33%)
Similarity:	173/314 - (55%)	Gaps:	19/314 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 AYNWAQYYELDDTYAWLQSLAQTNPGVVTLIEGGKTYQGRSILGVKITKGGETINGKAKPGIFLE 183
            :|::.:|:.:|:..||:..:.:.||.||:.:..|:||:.|:|..:||.....|    .|..|:::
Zfish    29 SYDYTKYHTMDEISAWMNQMQRENPDVVSTMTYGQTYEKRNITLLKIGFSSTT----PKKAIWMD 89

  Fly   184 AGIHAREWIAPAAATFIINQLLTS--EVENIKELAENYTWYVLPHANPDGYVYTHTTN--RLWRK 244
            .|||||||||||.....:.::|.|  ....:..|.:|..:|:.|..|.|||:|:...|  |||||
Zfish    90 CGIHAREWIAPAFCQHFVKEVLGSYKTDSRVNMLFKNLDFYITPVLNMDGYIYSWLNNSTRLWRK 154

  Fly   245 TRTP---YGSCFGADPNRNWGFHWNEVGASSSACSDTYAGPSAFSEIETLSLSKFIEGLKGKVQL 306
            :|:|   ..:|.|.|.|||:..:|..||.|.:.||:.|.|.:|.||.|..:::.|:...:..:..
Zfish   155 SRSPCHENSTCSGTDLNRNFYANWGMVGISRNCCSEVYNGATALSEPEAEAVTDFLGAHQNHLLC 219

  Fly   307 YLSLHAYSQYLLYPYGHTSDLPDNVADFEKVFDASIAAVNKRYGTTYTGGNIYDAIYPAAGASVD 371
            ||::|:|.|.:|.||||.:....|..:..:|..|:..|:...:|.:|..|:..|.:||.:|:|.|
Zfish   220 YLTIHSYGQLILVPYGHPNISAPNYDELMEVGLAAAKAIKAVHGKSYKVGSSPDVLYPNSGSSRD 284

  Fly   372 WA--YGTQDVRMAFCYELRPSSTSYLTGFKLPAEQIVPASEELLDSIVAMATEV 423
            :|  .|   :..:|.:|||.....   ||.||.:||.|..:|..:..:::...|
Zfish   285 FARLIG---IPYSFTFELRDEGQH---GFILPEDQIQPTCQEAYEGAMSIINYV 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17633	NP_609310.2	MpaA	7..374	CDD:225421	92/263 (35%)
		Propep_M14	34..105	CDD:280416
		M14_CP_A-B_like	125..423	CDD:199844	104/306 (34%)
cpo	NP_001139101.1	M14_CP_A-B_like	35..332	CDD:199844	104/306 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593522
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.780