DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4017 and AGBL4

DIOPT Version :9

Sequence 1:	NP_609309.1	Gene:	CG4017 / 34296	FlyBaseID:	FBgn0032143	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_011540610.1	Gene:	AGBL4 / 84871	HGNCID:	25892	Length:	531	Species:	Homo sapiens

Alignment Length:	320	Identity:	66/320 - (20%)
Similarity:	114/320 - (35%)	Gaps:	83/320 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 NRRSDDYSWSEYHELNDT--HRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHNDG---RAE 167
            :|..|.|.::..:....|  ..::.:|..:..|.......|||.:.|:|..|.|...|.   .||
Human   167 DREEDIYQFAYCYPYTYTRFQHYLDSLQKRNMDYFFREQLGQSVQQRKLDLLTITSPDNLREGAE 231

  Fly   168 KQSIFLEAGMHARE-----------------------------WIGPATATYFANELLSSQQQEI 203
            ::.:|:...:|..|                             |:.|....:..:      |..|
Human   232 QKVVFITGRVHPGETPSSFVCQGIPPGHWAALSSSFQNSPGIHWMSPGIIDFLVS------QHPI 290

  Fly   204 MNLARSY-VWYILPHANPDG-YVYTHKTNRMWRKTRSPQDKNCVGTDPNRNWDFHWREVGASSDP 266
            ..:.|.| |:.|.|..|||| |:..::.:.|             |.|.||:|
Human   291 ACVLREYLVFKIAPMLNPDGVYLGNYRCSLM-------------GFDLNRHW------------- 329

  Fly   267 CSESYAGPKAFSEPEVQTLSQFLKSV---PEPMFMF-LSLHSFSQLLL-YPYGHTSALPENHRQL 326
                 ..|..:..|.:..:.|.:..:   |:....| :.:|:.|.::. :.||:... .|...|.
Human   330 -----LDPSPWVHPTLHGVKQLIVQMYNDPKTSLEFYIDIHAHSTMMNGFMYGNIFE-DEERFQR 388

  Fly   327 EQIFNTAVGAMKRRYGTRYTGGNVYDAIYPAAGSSMDWAYGVLNVKYSFTYELRPSGYSF 386
            :.||...:......:....|..| .||:  .||:...:..|:|: ..|:.|.|..|.||:
Human   389 QAIFPKLLCQNAEDFSYSSTSFN-RDAV--KAGTGRRFLGGLLD-HTSYCYTLEVSFYSY 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4017	NP_609309.1	Propep_M14	30..97	CDD:280416
CG4017	NP_609309.1	M14_CP_A-B_like	119..415	CDD:199844	63/309 (20%)
AGBL4	XP_011540610.1	M14_AGBL4_like	190..475	CDD:133118	62/297 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810