DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4017 and Agbl4

DIOPT Version :9

Sequence 1:	NP_609309.1	Gene:	CG4017 / 34296	FlyBaseID:	FBgn0032143	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_011238954.1	Gene:	Agbl4 / 78933	MGIID:	1918244	Length:	552	Species:	Mus musculus

Alignment Length:	338	Identity:	78/338 - (23%)
Similarity:	128/338 - (37%)	Gaps:	78/338 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 NRRSDDYSWSEYHELNDT--HRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRI----NHNDGRA 166
            :|..|.|.::..:....|  ..::.:|..|..|.......|||.:.|:|..|.|    |..:| :
Mouse   167 DREDDIYQFAYCYPYTYTRFQHYLDSLQKKNMDYFFREQLGQSVQQRQLDLLTITSPENLREG-S 230

  Fly   167 EKQSIFLEAGMHAREWIGPATATYFA----NELLSSQQQEIMNLARSYVWYILPHANPDG-YVYT 226
            ||:.||:...:|..|     |.:.|.    .:.|.||......|....|:.|.|..|||| |:..
Mouse   231 EKKVIFITGRVHPGE-----TPSSFVCQGIIDFLVSQHPIARVLREHLVFKIAPMLNPDGVYLGN 290

  Fly   227 HKTNRMWRKTRSPQDKNCVGTDPNRNWDFHWREVGASSDPCSESYAGPKAFSEPEVQTLSQ-FLK 290
            ::.:.|             |.|.||:|                  ..|..::.|.:..:.| .:|
Mouse   291 YRCSLM-------------GFDLNRHW------------------LDPSPWAHPTLHGVKQLIIK 324

  Fly   291 SVPEP---MFMFLSLHSFSQLLL-YPYGHTSALPENHRQLEQIFNTAVGAMKRRYGTRYTGGNVY 351
            ...:|   :..::.:|:.|.::. :.||:... .|...|.:.||...:......:....|..| .
Mouse   325 MYNDPKTSLEFYIDIHAHSTMMNGFMYGNIFE-DEERFQRQSIFPKLLCQNAEDFSYTSTSFN-R 387

  Fly   352 DAIYPAAGSSMDWAYGVLNVKYSFTYELRPSGYSFWTGFRLPAAQIIPTGQET------------ 404
            ||:  .||:...:..|:|: ..|:.|.|..|.||:..|....|   :|..:|.
Mouse   388 DAV--KAGTGRRFLGGLLD-HSSYCYTLEVSFYSYIIGGTTAA---VPYTEEAYMKLGRNVARTF 446

  Fly   405 -----TDSLVEMI 412
                 .:||||.|
Mouse   447 LDYYRLNSLVEKI 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4017	NP_609309.1	Propep_M14	30..97	CDD:280416
CG4017	NP_609309.1	M14_CP_A-B_like	119..415	CDD:199844	75/327 (23%)
Agbl4	XP_011238954.1	Pepdidase_M14_N	65..>142	CDD:375499
Agbl4	XP_011238954.1	M14_AGBL4_like	199..450	CDD:349479	67/295 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900