DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4017 and cpb2

DIOPT Version :9

Sequence 1:	NP_609309.1	Gene:	CG4017 / 34296	FlyBaseID:	FBgn0032143	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001025617.1	Gene:	cpb2 / 595005	XenbaseID:	XB-GENE-969491	Length:	421	Species:	Xenopus tropicalis

Alignment Length:	426	Identity:	146/426 - (34%)
Similarity:	213/426 - (50%)	Gaps:	56/426 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 NILIFCL-----------AERQRFDNYKVYRVSPVKANQLEGLRSLEANSEDALVL----NNLHL 60
            |.||.|:           ||    |:.:|..|.|....|:|.|:::  .|:..:||    :|.|:
Frog     3 NYLIICILGLFVVDFQVSAE----DSDQVLYVLPRTDQQVEILKNI--TSQPEIVLWKPDSNEHI 61

  Fly    61 ---GPTDFLVAPDFDGT-----------FLKLVKDLDLSPELIDANAQTSLSLDIEPIADANRRS 111
               ....|.|...|..|           ::.||.:   :.|||:.......|         |:||
Frog    62 MKNKEVHFYVNESFIDTVKAELNESSILYMVLVNN---AQELIEQQTFNDTS---------NQRS 114

  Fly   112 DDYSWSEYHELNDTHRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHNDGRAEKQSIFLEAG 176
            ....:.:||.|.|.:.|||::|.|:.|::.....|.|:|.|.|..|:::..: :..|.:::::.|
Frog   115 ATSFYEQYHTLEDIYYWMQHMVEKHSDMLQRIHIGYSFENRPLYVLKVSGKE-KTAKHAVWIDCG 178

  Fly   177 MHAREWIGPATATYFANELLS--SQQQEIMNLARSYVWYILPHANPDGYVYTHKT-NRMWRKTRS 238
            :||||||.||...:|....:.  .....:..|.|...:||||..|.|||.::... ||||||.||
Frog   179 IHAREWISPAFCLWFVGHAVEYYGVDLSMTKLLRYLDFYILPVMNADGYQFSWTAKNRMWRKNRS 243

  Fly   239 PQDK-NCVGTDPNRNWDFHWREVGASSDPCSESYAGPKAFSEPEVQTLSQFLKSVPEPMFMFLSL 302
            ...| ||:|||.|||:|..|...|||||||.|.|.||.|.|||||..:..|||.....:..::::
Frog   244 KYTKSNCIGTDLNRNFDAGWCGPGASSDPCHEIYCGPYAESEPEVSAVVSFLKKHQNVVKGYITV 308

  Fly   303 HSFSQLLLYPYGHTSALPENHRQLEQIFNTAVGAMKRRYGTRYTGGNVYDAIYPAAGSSMDWAYG 367
            ||:||::|:||.:|:...::|.:|..:.......::.....:|..|...:.||.|.|.|.||||.
Frog   309 HSYSQMVLFPYSYTNKKSKDHDELLLLSKKVAEGIRSTSRNKYMYGAGAETIYLAPGGSDDWAYD 373

  Fly   368 VLNVKYSFTYELRPSGYSFWTGFRLPAAQIIPTGQE 403
             |.:|||||:|||..|   ..||.||...|.||..|
Frog   374 -LGIKYSFTFELRDKG---MYGFLLPPQLIKPTCSE 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4017	NP_609309.1	Propep_M14	30..97	CDD:280416	19/84 (23%)
CG4017	NP_609309.1	M14_CP_A-B_like	119..415	CDD:199844	115/289 (40%)
cpb2	NP_001025617.1	Propep_M14	33..104	CDD:366995	17/75 (23%)
cpb2	NP_001025617.1	M14_CPB2	118..418	CDD:349465	115/293 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	240	1.000	Domainoid score	I2216
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm9413
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.950