Protein Alignment CG4017 and CPA4

DIOPT Version :10

• Sequence 1: NP_609309.1
• Gene: CG4017 / 34296
• FlyBaseID: FBgn0032143
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_057436.2
• Gene: CPA4 / 51200
• HGNCID: 15740
• Length: 421
• Species: Homo sapiens
• Alignment Length: 417
• Identity: 145/417 - (34%)
• Similarity: 224/417 - (53%)
• Gaps: 34/417 - (8%)

  Fly     7 LLSVNILI-FCLAERQRFDNYKVYRVSPVKANQLEGLRSLEANSEDALVLNNLHLG--------- 61
            :|.:..|| ..:..:::|...:|.|::....:::..|..| .||      |||.|.
Human     4 ILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQL-VNS------NNLKLNFWKSPSSFN 61

  Fly    62 -PTDFLVAPDFDGTFLKLVKDLDLSPELIDANAQTSLSLDIEPI---ADANRRSDDYSWSEYHEL 122
             |.|.||.......|...::...|...:...:.|..|..:.:.:   ....|.|:::::..||.|
Human    62 RPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYGAYHSL 126

  Fly   123 NDTHRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHNDGRAEKQSIFLEAGMHAREWIGPAT 187
            ...:..|.|:...:||:......|.|:|.|.:..|:.:...| ..:.:::|.||:|:||||..||
Human   127 EAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKG-VRRPAVWLNAGIHSREWISQAT 190

  Fly   188 ATYFANELLSSQQQE--IMNLARSYVWYILPHANPDGYVYTHKTNRMWRKTRSPQ-DKNCVGTDP 249
            |.:.|.:::|..|::  |.::......::||.|||||||||...||:||||||.. ..:|:|.||
Human   191 AIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGADP 255

  Fly   250 NRNWDFHWREVGASSDPCSESYAGPKAFSEPEVQTLSQFLKSVPEPMFM-FLSLHSFSQLLLYPY 313
            ||||:..:...|||.:||||.|.||.|.||.||:::..|::.  ...|. |:.|||:||||:|||
Human   256 NRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQK--HGNFKGFIDLHSYSQLLMYPY 318

  Fly   314 GHTSALPENHRQLEQIFNTAVGAMKRRYGTRYTGGNVYDAIYPAAGSSMDWAYGVLNVKYSFTYE 378
            |::.....:..:|:::...|..|:....||.|..|.....:|||:|||:||||. ..:|::||:|
Human   319 GYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTTVYPASGSSIDWAYD-NGIKFAFTFE 382

  Fly   379 LRPSG-YSFWTGFRLPAAQIIPTGQET 404
            ||.:| |    ||.|||.|||||.:||
Human   383 LRDTGTY----GFLLPANQIIPTAEET 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4017	NP_609309.1	Propep_M14	29..97	CDD:460505	16/77 (21%)
		M14_CP_A-B_like	119..417	CDD:349433	121/291 (42%)
CPA4	NP_057436.2	Propep_M14	27..101	CDD:460505	17/80 (21%)
		M14_CPA	118..419	CDD:349442	121/296 (41%)