DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4017 and Cpa5

DIOPT Version :9

Sequence 1:	NP_609309.1	Gene:	CG4017 / 34296	FlyBaseID:	FBgn0032143	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001002808.2	Gene:	Cpa5 / 408212	RGDID:	1303098	Length:	436	Species:	Rattus norvegicus

Alignment Length:	422	Identity:	133/422 - (31%)
Similarity:	229/422 - (54%)	Gaps:	28/422 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LLSVNILIFCLAERQRFDNYKVYRVSPVKANQLEGLRSLEANSEDALVLNNLHLGPTDFLVAPDF 71
            ||..|.::.....:..|...:|.||......||..||.||......:   :...||....:..|.
  Rat    21 LLFCNFILAVAWGQVNFTGDQVLRVLAKNEKQLSLLRDLEIQKPQKV---DFWRGPARPSLPVDM 82

  Fly    72 DGTFLKL------VKDLDLSPELIDANAQTSLSLDIEPIADA---NRRSDDYSWSEYHELNDTHR 127
            ...|.:|      :|...|:..::..:.|..|..:.:.:|.:   .|.::.:|:|.||.|.:.:.
  Rat    83 RVPFSELPSVKAYLKSHGLAYSVMIKDIQVLLDEERDAMARSRRLERSTNGFSYSSYHTLEEIYN 147

  Fly   128 WMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHNDGRAEKQSIFLEAGMHAREWIGPATATYFA 192
            |:.|.|.::.::||....|:|:|.|.:|.|:.  :.|...:.:|:::.|:|:||||..||..:.:
  Rat   148 WIDNFVAEHSNLVSKIHIGKSFENRSILVLKF--STGGPNRTAIWIDTGIHSREWITHATGIWIS 210

  Fly   193 NELLSSQQQE-----IMNLARSYVWYILPHANPDGYVYTHKTNRMWRKTRSPQDK-NCVGTDPNR 251
            .:::::..::     ::|....::..:   .||||:.:||..||:|||.:|.|.. .|||.|.||
  Rat   211 QKIVNAYSKDHVLKKVLNTMDIFIEIV---TNPDGFAFTHSMNRLWRKNKSIQPGIVCVGVDLNR 272

  Fly   252 NWDFHWREVGASSDPCSESYAGPKAFSEPEVQTLSQFLKSVPEPMFMFLSLHSFSQLLLYPYGHT 316
            ||...:...|::.:||||:|.||...|||||..:..|:........| :|:||:||:::|||||:
  Rat   273 NWRTGFGGNGSNKNPCSETYRGPAPESEPEVAAIVAFITGHGNFKAM-ISIHSYSQMVMYPYGHS 336

  Fly   317 SALPENHRQLEQIFNTAVGAMKRRYGTRYTGGNVYDAIYPAAGSSMDWAYGVLNVKYSFTYELRP 381
            .....||::|.::...||.|:.:.:|..|..|::...:|.|:|.::||||. ..:||:|::|||.
  Rat   337 LEPVPNHKELFELAKDAVKALYKVHGMEYIFGSISTTLYSASGITVDWAYD-SGIKYAFSFELRD 400

  Fly   382 SGYSFWTGFRLPAAQIIPTGQETTDSLVEMIK 413
            :|.   .||.|||:||:||.:||..:|..::|
  Rat   401 TGQ---YGFLLPASQIVPTAEETWMALRTIMK 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4017	NP_609309.1	Propep_M14	30..97	CDD:280416	16/72 (22%)
CG4017	NP_609309.1	M14_CP_A-B_like	119..415	CDD:199844	107/301 (36%)
Cpa5	NP_001002808.2	Propep_M14	48..117	CDD:396700	15/71 (21%)
Cpa5	NP_001002808.2	M14_CPA	134..434	CDD:349442	109/306 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351682
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	262	1.000	Inparanoid score	I3014
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm8990
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.800