DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4017 and CG8560

DIOPT Version :9

Sequence 1:	NP_609309.1	Gene:	CG4017 / 34296	FlyBaseID:	FBgn0032143	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001261516.1	Gene:	CG8560 / 38830	FlyBaseID:	FBgn0035781	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	435	Identity:	159/435 - (36%)
Similarity:	228/435 - (52%)	Gaps:	49/435 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLLLLLSVNILIFCLAERQRFDNYKVYRVSPVKANQLEGL---------------RSLEANSEDA 52
            ::|||.||.:.:      :.:|.||:|.::...|.:.:.|               |||:|:|.
  Fly     7 VVLLLASVALAV------ENYDGYKIYDINARNAFEKQLLLRLSGNEAYDFFDLPRSLDASSR-- 63

  Fly    53 LVLNNLHLGPTDFLVAPDFDGTFLKLVKDLDLSPELIDANAQTSLSLDIEPIAD---ANRRSDD- 113
                        .:|.|:....|..|::...::..:|:.|...||..:.:...:   .|.||.:
  Fly    64 ------------VMVKPEDQEGFEHLLEKYGVNYSVINENFGESLRQERDENQNQRLMNLRSAER 116

  Fly   114 -YSWSEYHELNDTHRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHNDGRAEKQSIFLEAGM 177
             .|:..:|...:.:.::..|...||..|||.|||:|||.|::..:.|.:.||:..|..:||:||:
  Fly   117 SVSFKAFHRHAEINAYLDELAAAYPSRVSVQVAGKSYENRDIKTITITNGDGKTGKNVVFLDAGI 181

  Fly   178 HAREWIGPATATYFANELLSSQQQEIMNLARSYVWYILPHANPDGYVYTHKTNRMWRKTRSPQDK 242
            ||||||..|.|.|..::|:.:.... ..|.:.:.|.|||..|||||.|:|.|.|||||||.|...
  Fly   182 HAREWIAHAGALYVIHQLVENFAAN-SELLKDFDWVILPVVNPDGYEYSHTTTRMWRKTRKPISS 245

  Fly   243 NCVGTDPNRNWDFHWREVGASSDPCSESYAGPKAFSEPEVQTLSQFLKSVPEPMFMFLSLHSFSQ 307
            .|.|||.|||:||||.||||||..||:::.|..||||||.|.:...|.|:......:|:|||:..
  Fly   246 ACYGTDANRNFDFHWGEVGASSYSCSDTFKGETAFSEPETQLIRDILLSLTGRGKFYLTLHSYGN 310

  Fly   308 LLLYPYGHTSALPENHRQLEQIFNTAVGAMKRRYGTRYTGGNVYDAIYPAAGSSMDWAYGVLNVK 372
            .||||:|.|||||.:.|..:::......|:|...||:||.|:..:.:|.|||.|.|:|:||.|..
  Fly   311 YLLYPWGWTSALPSSWRDNDEVAQGGADAIKSATGTKYTVGSSTNVLYAAAGGSDDYAFGVANFP 375

  Fly   373 YSFTYELRPSGYSFWTGFRLPAAQIIPTGQETTDSLVEMIKAAAQ 417
            .|.|.||...|    |||....:||.....||...    |||.||
  Fly   376 VSITMELPAGG----TGFNPSTSQIEGFVSETWVG----IKAMAQ 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4017	NP_609309.1	Propep_M14	30..97	CDD:280416	13/81 (16%)
CG4017	NP_609309.1	M14_CP_A-B_like	119..415	CDD:199844	128/295 (43%)
CG8560	NP_001261516.1	Propep_M14	29..98	CDD:280416	15/82 (18%)
CG8560	NP_001261516.1	M14_CP_A-B_like	123..414	CDD:199844	131/299 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467011
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	239	1.000	Inparanoid score	I2114
Isobase	1	0.950	-	0	Normalized mean entropy	S1851
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	11	10.750