DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4017 and Agbl5

DIOPT Version :9

Sequence 1:	NP_609309.1	Gene:	CG4017 / 34296	FlyBaseID:	FBgn0032143	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_038968402.1	Gene:	Agbl5 / 362710	RGDID:	1598311	Length:	901	Species:	Rattus norvegicus

Alignment Length:	392	Identity:	74/392 - (18%)
Similarity:	124/392 - (31%)	Gaps:	160/392 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 YSWSEYHELNDTHRWMQNLVGKYPDVVSVFVA--GQSYEGRELL-----GLRI------------ 159
            :|:|:..:|      :..|..::|:..|...:  ...|..||||     |||:
  Rat   159 FSYSDCQDL------LSQLDQRFPENYSAHSSPLDSIYYHRELLCYSLDGLRVDLLTITSCHGLR 217

  Fly   160 NHNDGRAE----------------KQSIFLEAGMHAREWIGPATATYFANELLSSQQQEIMNLAR 208
            :..:.|.|                |:..||.:.:|..|.........|.:.:|.........|.|
  Rat   218 DDREPRLEQLFPDVGTPRPFRFTGKRIFFLSSRVHPGETPSSFVFNGFLDFILRPDDPRAQTLRR 282

  Fly   209 SYVWYILPHANPDGYV------------------------------------YTHKTNRMWRKTR 237
            .:|:.::|..||||.|                                    |.|..:|:..|..
  Rat   283 LFVFKLIPMLNPDGVVRGHYRTDSRGVNLNRQYLKPDAVLHPAIYGAKAVLLYHHVHSRLNSKNP 347

  Fly   238 SPQDKNCVGTDP-----------NRNWDFH------------WREVGASSDPCSESYAGPKAFSE 279
            |.|..:.:...|           |.:.:.|            |.|    ::|..|.       ::
  Rat   348 SNQQPSSLHLPPEVPLSDLEKANNLHNELHLGQSPDGENHDRWTE----TEPTEEK-------TD 401

  Fly   280 PEVQTLSQFLKSVPEP-----------MFMFLSLHSF-SQLLLYPYGHTSALPENHRQLEQI--- 329
            | |..:.|.:..:.||           :..::.||.. |:...:.||  ::..:...|:|.:
  Rat   402 P-VWIMPQPIPELEEPAPDAIPPKESGVAYYVDLHGHASKRGCFMYG--NSFSDESTQVENMLYP 463

  Fly   330 ----FNTA-------------VGAMKRRYGTRYTG-GNVYDAIYPAAGSSMDWAYGVLNVKYSFT 376
                .|:|             :.|..||.|....| |.|  |||.|:|           :.:|:|
  Rat   464 KLISLNSAHFDFQGCNFSEKNMYARDRRDGQSKEGSGRV--AIYKASG-----------IIHSYT 515

  Fly   377 YE 378
            .|
  Rat   516 LE 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4017	NP_609309.1	Propep_M14	30..97	CDD:280416
CG4017	NP_609309.1	M14_CP_A-B_like	119..415	CDD:199844	72/387 (19%)
Agbl5	XP_038968402.1	Pepdidase_M14_N	10..155	CDD:407865
Agbl5	XP_038968402.1	M14_AGBL5_like	183..575	CDD:349455	68/362 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900