DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4017 and CG3108

DIOPT Version :9

Sequence 1:	NP_609309.1	Gene:	CG4017 / 34296	FlyBaseID:	FBgn0032143	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster

Alignment Length:	422	Identity:	145/422 - (34%)
Similarity:	221/422 - (52%)	Gaps:	35/422 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 AERQRFDNYKVYRV------SPVKANQL----EGLRSLEANSEDALVLNNLHLGPTDFLVAPDFD 72
            |..:|:|..:|:|:      ....|::|    :|....|...|            .|:|:.|...
  Fly   718 AHLRRYDGAQVWRIVVQTDKDKRMADELQSKYDGQLWKEVKQE------------VDYLLKPQVL 770

  Fly    73 GTFLKLVKDLDLSPELIDANAQTSLSLD---IEPIAD-ANRRSDDYSWSEYHELNDTHRWMQNLV 133
            ....:.::..:||..::..|.|..:..:   .|.||: .||:....:|..||.|.|.|.::..:.
  Fly   771 AAAERHIRAANLSRIVLIDNLQRVIEKENPPAEKIAELQNRKGHRLTWQAYHRLEDIHGFIDYMA 835

  Fly   134 GKYPDVVSVFVAGQSYEGRELLGLRINHNDGRAEKQSIFLEAGMHAREWIGPATATYFANELLSS 198
            ..|||:.|..:.|.|.|.|.|..|:|  ::|.|....|:::.||||||||.|||.||.||:|:..
  Fly   836 KTYPDICSTEIIGYSVEKRPLKILKI--SNGNARNPGIWIDGGMHAREWISPATVTYIANQLVEG 898

  Fly   199 QQQEIMNLARSYVWYILPHANPDGYVYTHKTNRMWRKTRSPQDKNCVGTDPNRNWDFHWREVGAS 263
             .:::....||..|||.|.||||||.|:|.|:|:|||......:.|.|.|.|||:.:.|...|.|
  Fly   899 -WEDLPEHMRSINWYIHPVANPDGYEYSHTTDRLWRKNMRAHGRQCPGVDLNRNFGYKWGGKGTS 962

  Fly   264 SDPCSESYAGPKAFSEPEVQTLSQFLKSVPEPMFM-FLSLHSFSQLLLYPYGHTSALPENHRQLE 327
            :.|||::|.|.|||||||...:|:|:...|...|. :||.||:.|.:|||:|:...|.::...|:
  Fly   963 ASPCSQTYRGSKAFSEPETFYISKFISGFPRETFQAYLSFHSYGQYILYPWGYDYQLTQDRADLD 1027

  Fly   328 QIFNTAVGAMKRRYGTRYTGGNVYDAIYPAAGSSMDWAYGVLNVKYSFTYELRPSG-YSFWTGFR 391
            ::...|..::.:..|.:||.|:....:|||||.|.|||.|:..:||::|.|:..:| |    ||.
  Fly  1028 RVARQAGTSITKSTGVKYTVGSSATTLYPAAGGSDDWAKGIAGIKYAYTIEMGDTGRY----GFV 1088

  Fly   392 LPAAQIIPTGQETTDSLVEMIKAAAQIEGYKI 423
            |||..|...|::.......:.:|.||..|..:
  Fly  1089 LPARFIQYNGKDGVTFADTVARAIAQGRGKSV 1120

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4017	NP_609309.1	Propep_M14	30..97	CDD:280416	13/76 (17%)
CG4017	NP_609309.1	M14_CP_A-B_like	119..415	CDD:199844	118/297 (40%)
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416	13/78 (17%)
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844	118/297 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466963
Domainoid	1	1.000	225	1.000	Domainoid score	I2535
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
	11	10.780