DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4017 and Cpa6

DIOPT Version :9

Sequence 1:	NP_609309.1	Gene:	CG4017 / 34296	FlyBaseID:	FBgn0032143	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_038965675.1	Gene:	Cpa6 / 312913	RGDID:	1311764	Length:	290	Species:	Rattus norvegicus

Alignment Length:	288	Identity:	111/288 - (38%)
Similarity:	166/288 - (57%)	Gaps:	18/288 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 HELNDTHRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHNDGRAEKQSIFLEAGMHAREWIG 184
            |.||.|.          |.:|.||..|:|:|||.||.:::... .:..|::::::.|:|||||||
  Rat     2 HHLNQTQ----------PGLVRVFPIGRSFEGRSLLIIQLGRK-SQVYKRAVWIDCGIHAREWIG 55

  Fly   185 PATATYFANELLSSQQQE--IMNLARSYVWYILPHANPDGYVYTHKTNRMWRKTRSPQDK-NCVG 246
            ||...:|..|.:.:.:.:  :..:.....:||:|..|.|||.::...:|.||||||...| :|.|
  Rat    56 PAFCQWFVKEAILTYKTDPAMRKMLNHLYFYIMPVLNVDGYHFSWTHDRFWRKTRSRNSKFHCRG 120

  Fly   247 TDPNRNWDFHWREVGASSDPCSESYAGPKAFSEPEVQTLSQFLKSVPEPMFMFLSLHSFSQLLLY 311
            .|.||||...|.:.|||:|||.::|.||...|||||:.::.||:...:.:..:||.|:::|:|||
  Rat   121 VDANRNWKVKWCDEGASADPCDDTYCGPFPESEPEVKAVANFLRKHRKRIRAYLSFHAYAQMLLY 185

  Fly   312 PYGHTSALPENHRQLEQIFNTAVGAMKRRYGTRYTGGNVYDAIYPAAGSSMDWAYGVLNVKYSFT 376
            ||.:..|...|...:|...:.||.|::..:|.||..|.....:|.::|:|||||| ...:.|||.
  Rat   186 PYSYKHATIPNFSCVEFAAHKAVKALRSVHGIRYRHGPASQTLYVSSGNSMDWAY-KNGIPYSFA 249

  Fly   377 YELRPSGYSFWTGFRLPAAQIIPTGQET 404
            :|||.:||   .||.||...|.||..||
  Rat   250 FELRDTGY---FGFLLPEMLIKPTCTET 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4017	NP_609309.1	Propep_M14	30..97	CDD:280416
CG4017	NP_609309.1	M14_CP_A-B_like	119..415	CDD:199844	111/288 (39%)
Cpa6	XP_038965675.1	Peptidase_M14_like	1..289	CDD:416253	111/288 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351704
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	262	1.000	Inparanoid score	I3014
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.800