DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4017 and ZC434.9

DIOPT Version :9

Sequence 1:	NP_609309.1	Gene:	CG4017 / 34296	FlyBaseID:	FBgn0032143	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001251356.1	Gene:	ZC434.9 / 172908	WormBaseID:	WBGene00013895	Length:	720	Species:	Caenorhabditis elegans

Alignment Length:	463	Identity:	149/463 - (32%)
Similarity:	236/463 - (50%)	Gaps:	61/463 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LLLLLSVNILIFCLAERQRFDNYKVYRVSPVKANQLEGLRSLEANSEDALVLNNLHLGPTDFLVA 68
            ||:|:|...:...:|: .:...::|.|.......||:.||.:...::..|          ||...
Worm    12 LLILISAFAINAEIAD-DKPPKFQVLRAHATDVPQLKALRDIHERTQHDL----------DFWQT 65

  Fly    69 PDFDGTFLKLVKDLDLSPELIDA---NAQTSLSLDIEPIAD-----------------ANRRSDD 113
            |...|....::.|.| ..|.:|:   |:..|..:.||.:..                 :.|..::
Worm    66 PSKVGHRADIMVDED-RMEWLDSVLKNSNISYDVIIEDVGKLILEKEHGPPRFSNLLFSKRMHNE 129

  Fly   114 ------YSWSEYHELNDTHRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHNDGRAEKQSIF 172
                  |.:.|||.......||:::..||||...||..|.:.|||.:.|::|.....|.:|:..:
Worm   130 GGNRARYGFGEYHSYQTICDWMKDIERKYPDKAKVFTMGTTSEGRPIQGIKIGSQVWRNDKRIFW 194

  Fly   173 LEAGMHAREWIGPATATYFANELLSSQQQEIMNLARSYV----WYILPHANPDGYVYTHK----T 229
            ::.|:|||||....||.:|.:.|::....:  :|.|:.|    :||||.||||||.|:..    .
Worm   195 IDGGIHAREWAAVHTALWFIDRLIADYNDD--SLVRAAVDRLNFYILPVANPDGYEYSRSDVSPM 257

  Fly   230 NRMWRKTRSP---------QDKNCVGTDPNRNWDFHWREVGASSDPCSESYAGPKAFSEPEVQTL 285
            .|:|||.|:.         :|:.|.|.|.|||:|:|:.|.|:|:|.|||.|.|..||||.|.:::
Worm   258 IRLWRKNRAGVVCKKDRWFRDRCCGGVDLNRNYDWHFGETGSSTDKCSEIYQGSSAFSESETRSM 322

  Fly   286 SQFLKS--VPEPMFMFLSLHSFSQLLLYPYGHT-SALPENHRQLEQIFNTAVGAMKRRYGTRYTG 347
            ..||.|  :...:..|::||::||:.::||.|. .::|.:..:|:::...||.|::..|||:|..
Worm   323 RDFLTSSELNGKIDAFITLHTYSQMWIHPYSHARKSVPADVAELQRVGRAAVAALENTYGTKYKF 387

  Fly   348 GNVYDAIYPAAGSSMDWAYGVLNVKYSFTYELRPSGYSFWTGFRLPAAQIIPTGQETTDSLVEMI 412
            |...|.:||:||.|.|||.|.|.:||.:..|||| |...|.||.|...|:|||.:||.:.:..:|
Worm   388 GTGSDILYPSAGGSDDWAKGTLRIKYVYLLELRP-GEDVWDGFILDQHQLIPTAKETWNGIKVVI 451

  Fly   413 KAAAQIEG 420
            :|..:..|
Worm   452 RAVTEQAG 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4017	NP_609309.1	Propep_M14	30..97	CDD:280416	15/69 (22%)
CG4017	NP_609309.1	M14_CP_A-B_like	119..415	CDD:199844	120/315 (38%)
ZC434.9	NP_001251356.1	Propep_M14	45..111	CDD:366995	17/76 (22%)
		M14_CP_A-B_like	141..454	CDD:349433	120/315 (38%)
		ShK	682..719	CDD:366702
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm4737
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.820