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Protein Alignment CG4017 and CPB2

DIOPT Version :9

Sequence 1:	NP_609309.1	Gene:	CG4017 / 34296	FlyBaseID:	FBgn0032143	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001863.3	Gene:	CPB2 / 1361	HGNCID:	2300	Length:	423	Species:	Homo sapiens

Alignment Length:	425	Identity:	149/425 - (35%)
Similarity:	228/425 - (53%)	Gaps:	40/425 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLLLLLLSVNILIFCLAERQRFDNYKVYRVSPVKANQLEGLRSLEANSE---------DALV-L 55
            |||..|.:.|.|::||......|.:.:|....|..:.|::.|::|....|         |.:| .
Human     1 MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKK 65

  Fly    56 NNLHLGPTDFLVAPDFDGTFLKL-VKDLDLSPELIDAN--AQTSLSLD-IEPIADANRRSDDYSW 116
            ..:|.    |:.|.|.|.....| |..:..|..|.|..  .|..:|.| :.|.|.|:      .:
Human    66 KQVHF----FVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASAS------YY 120

  Fly   117 SEYHELNDTHRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHNDGRAEKQSIFLEAGMHARE 181
            .:||.||:.:.|::.:..::||:::....|.|:|...|..|:::..: :|.|.:|:::.|:||||
Human   121 EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKE-QAAKNAIWIDCGIHARE 184

  Fly   182 WIGPATATYFANELLSSQQQEIM----NLARSYVWYILPHANPDGYVYTHKTNRMWRKTRSPQDK 242
            ||.||...:|...:  :|...|:    ||.|...:|::|..|.|||.|:.|.||||||.||....
Human   185 WISPAFCLWFIGHI--TQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYAN 247

  Fly   243 N-CVGTDPNRNW-DFHWREVGASSDPCSESYAGPKAFSEPEVQTLSQFLKSVPEPMFMFLSLHSF 305
            | |:|||.|||: ..||.|.||||..|||:|.|....|||||:.::.||:.....:..::|:||:
Human   248 NHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSY 312

  Fly   306 SQLLLYPYGHTSALPENHRQLEQIFNTAVGAMKR-RYGTRYTGGNVYDAIYPAAGSSMDWAYGVL 369
            ||.:::||.:|.:..::|.:|..:.:.||.|::: ...||||.|:..:.:|.|.|...||.|. |
Human   313 SQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYD-L 376

  Fly   370 NVKYSFTYELRPSG-YSFWTGFRLPAAQIIPTGQE 403
            .:|||||.|||.:| |    ||.||...|.||.:|
Human   377 GIKYSFTIELRDTGTY----GFLLPERYIKPTCRE 407

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.