Protein Alignment CG4017 and CPB2

DIOPT Version :10

• Sequence 1: NP_609309.1
• Gene: CG4017 / 34296
• FlyBaseID: FBgn0032143
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001863.3
• Gene: CPB2 / 1361
• HGNCID: 2300
• Length: 423
• Species: Homo sapiens
• Alignment Length: 425
• Identity: 149/425 - (35%)
• Similarity: 228/425 - (53%)
• Gaps: 40/425 - (9%)

  Fly     1 MKLLLLLLSVNILIFCLAERQRFDNYKVYRVSPVKANQLEGLRSLEANSE---------DALV-L 55
            |||..|.:.|.|::||......|.:.:|....|..:.|::.|::|....|         |.:| .
Human     1 MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKK 65

  Fly    56 NNLHLGPTDFLVAPDFDGTFLKL-VKDLDLSPELIDAN--AQTSLSLD-IEPIADANRRSDDYSW 116
            ..:|.    |:.|.|.|.....| |..:..|..|.|..  .|..:|.| :.|.|.|:      .:
Human    66 KQVHF----FVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASAS------YY 120

  Fly   117 SEYHELNDTHRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHNDGRAEKQSIFLEAGMHARE 181
            .:||.||:.:.|::.:..::||:::....|.|:|...|..|:::..: :|.|.:|:::.|:||||
Human   121 EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKE-QAAKNAIWIDCGIHARE 184

  Fly   182 WIGPATATYFANELLSSQQQEIM----NLARSYVWYILPHANPDGYVYTHKTNRMWRKTRSPQDK 242
            ||.||...:|...:  :|...|:    ||.|...:|::|..|.|||.|:.|.||||||.||....
Human   185 WISPAFCLWFIGHI--TQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYAN 247

  Fly   243 N-CVGTDPNRNW-DFHWREVGASSDPCSESYAGPKAFSEPEVQTLSQFLKSVPEPMFMFLSLHSF 305
            | |:|||.|||: ..||.|.||||..|||:|.|....|||||:.::.||:.....:..::|:||:
Human   248 NHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSY 312

  Fly   306 SQLLLYPYGHTSALPENHRQLEQIFNTAVGAMKR-RYGTRYTGGNVYDAIYPAAGSSMDWAYGVL 369
            ||.:::||.:|.:..::|.:|..:.:.||.|::: ...||||.|:..:.:|.|.|...||.|. |
Human   313 SQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYD-L 376

  Fly   370 NVKYSFTYELRPSG-YSFWTGFRLPAAQIIPTGQE 403
            .:|||||.|||.:| |    ||.||...|.||.:|
Human   377 GIKYSFTIELRDTGTY----GFLLPERYIKPTCRE 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4017	NP_609309.1	Propep_M14	29..97	CDD:460505	18/80 (23%)
		M14_CP_A-B_like	119..417	CDD:349433	116/293 (40%)
CPB2	NP_001863.3	Propep_M14	33..105	CDD:460505	18/75 (24%)
		M14_CPB2	119..420	CDD:349465	116/297 (39%)