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Protein Alignment CG4017 and CPA2

DIOPT Version :9

Sequence 1:	NP_609309.1	Gene:	CG4017 / 34296	FlyBaseID:	FBgn0032143	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001860.2	Gene:	CPA2 / 1358	HGNCID:	2297	Length:	419	Species:	Homo sapiens

Alignment Length:	435	Identity:	153/435 - (35%)
Similarity:	238/435 - (54%)	Gaps:	65/435 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLLLLLLSVNILIFCLAERQRFDNYKVYRVSPVKANQLEGLRSLEANSEDALVLNNLHLGPTDF 65
            |:|:|...::...|:||   :.|...:|..:.|....|::.|..|||..         || ..||
Human     3 MRLILFFGALFGHIYCL---ETFVGDQVLEIVPSNEEQIKNLLQLEAQE---------HL-QLDF 54

  Fly    66 LVAPDFDG----------------TFLK--------LVKDLDLSPELIDANAQTSLSLDIEPIAD 106
            ..:|...|                .||:        :::|:.:   |:|...:..|
Human    55 WKSPTTPGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQV---LLDKENEEML--------- 107

  Fly   107 ANR---RSDDYSWSEYHELNDTHRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHNDGRAEK 168
            .||   ||.::::..||.|.:..:.|.|||.::|.:||....|.|:|.|.:..|:.:..   .:|
Human   108 FNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTG---GDK 169

  Fly   169 QSIFLEAGMHAREWIGPATATYFANELLS--SQQQEIMNLARSYVWYILPHANPDGYVYTHKTNR 231
            .:|:|:||:|||||:..|||.:.||:::|  .:...|.::..:...::||..||||||::...||
Human   170 PAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNR 234

  Fly   232 MWRKTRSPQDKN-CVGTDPNRNWDFHWREVGASSDPCSESYAGPKAFSEPEVQTLSQFLKSVPEP 295
            |||||||....: |||.|||||||..:...||||:|||:||.||.|.||.||:::..|:||..:
Human   235 MWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGK- 298

  Fly   296 MFMFLSLHSFSQLLLYPYGHTSALPENHRQLEQIFNTAVGAMKRRYGTRYTGGNVYDAIYPAAGS 360
            :..|::|||:||||::|||:.....::..:|.::...|..:::..:||:|..|.:...||.|:|.
Human   299 VKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGG 363

  Fly   361 SMDWAYGVLNVKYSFTYELRPSG-YSFWTGFRLPAAQIIPTGQET 404
            |:||:|. ..:||||.:|||.:| |    ||.|||.||:||.:||
Human   364 SIDWSYD-YGIKYSFAFELRDTGRY----GFLLPARQILPTAEET 403

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.