DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4017 and AGBL1

DIOPT Version :9

Sequence 1:	NP_609309.1	Gene:	CG4017 / 34296	FlyBaseID:	FBgn0032143	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001373023.1	Gene:	AGBL1 / 123624	HGNCID:	26504	Length:	1121	Species:	Homo sapiens

Alignment Length:	183	Identity:	42/183 - (22%)
Similarity:	63/183 - (34%)	Gaps:	59/183 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 LEAGMHARE----WIGPATATYFANELLSSQQQEIMNLARSYVWYILPHANPDGYVYTHKTNRMW 233
            :.|.:|..|    |:...|.     |.|.|.......|..::::.|:|..||||.:     |...
Human   799 ITARVHPGESNASWVMKGTL-----EFLVSSDPVARLLRENFIFKIIPMLNPDGVI-----NGNH 853

  Fly   234 RKTRSPQDKNCVGTDPNRNWDFHWREVGASSDPCSESYAGPKAFSEPEV---QTLSQFLKSVPEP 295
            |.:.|       |.|.||.|                  ..|.|..:|.:   :.|...|.|:...
Human   854 RCSLS-------GEDLNRQW------------------LSPSAHLQPTIYHAKGLLYHLSSIGRS 893

  Fly   296 MFMFLSLHSFSQ---LLLY-------------PYGHTSALPE-NHRQLEQIFN 331
            ..:|...|..||   :.||             ..|.::.|.| |:|.|.:|.:
Human   894 PVVFCDFHGHSQKKNVFLYGCSIKETLWQAACTVGTSTILEEVNYRTLPKILD 946

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4017	NP_609309.1	Propep_M14	30..97	CDD:280416
CG4017	NP_609309.1	M14_CP_A-B_like	119..415	CDD:199844	42/183 (23%)
AGBL1	NP_001373023.1	Pepdidase_M14_N	596..730	CDD:407865
AGBL1	NP_001373023.1	M14_Nna1	754..1019	CDD:349477	42/183 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900