DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4017 and cpo.1

DIOPT Version :9

Sequence 1:	NP_609309.1	Gene:	CG4017 / 34296	FlyBaseID:	FBgn0032143	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_031748368.1	Gene:	cpo.1 / 100145253	XenbaseID:	XB-GENE-989447	Length:	451	Species:	Xenopus tropicalis

Alignment Length:	363	Identity:	118/363 - (32%)
Similarity:	199/363 - (54%)	Gaps:	34/363 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 NLHLGPTDFLVAPDFDGTFLKLVKDLDLSPELIDANAQTSLSLDIEPIADANRRSD---DYSWSE 118
            |||          .:...|..::||:.   :|||::          .:.|..|:..   ::.::.
Frog    85 NLH----------QYSIPFEVMIKDVQ---KLIDSS----------NVGDYRRQKKILAEFDYTT 126

  Fly   119 YHELNDTHRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHNDGRAEKQSIFLEAGMHAREWI 183
            ||.:::.::||..:...|.|:||:...|.:||.|.:...:|.....: :|:.|:::.|:||||||
Frog   127 YHPMDEIYQWMDQVKEAYSDLVSMHYLGSTYELRPIYYFKIGWPSDK-QKKIIWMDCGIHAREWI 190

  Fly   184 GPATATYFANELLSSQQQE--IMNLARSYVWYILPHANPDGYVYTHKTNRMWRKTRSPQDK-NCV 245
            ..|...:|..|:|.:.:..  :..:..:..:||:|..|.||:||:...||:|||:|||.:. :|.
Frog   191 AVAYCQWFVKEILETHKTNPLLQKVLHNIDFYIVPVLNIDGFVYSWNVNRLWRKSRSPHNNGSCY 255

  Fly   246 GTDPNRNWDFHWREVGASSDPCSESYAGPKAFSEPEVQTLSQFLKSVPEPMFMFLSLHSFSQLLL 310
            |.|.|||::..|..:|||::...|:|.|....|||||..:|:.|.|:...:..||::||:.||||
Frog   256 GVDLNRNFNSKWGSIGASNNCRDETYCGTGPASEPEVNAVSKLLGSLKSDVLCFLTIHSYGQLLL 320

  Fly   311 YPYGHTSALPENHRQLEQIFNTAVGAMKRRYGTRYTGGNVYDAIYPAAGSSMDWAYGVLNVKYSF 375
            .|||:|.....||.::..:...|...::.::||.|..|:....:|..:|||.|||.. |.:.:|:
Frog   321 LPYGYTKDPSINHEEMINVAQKAAAKLQEKHGTEYRVGSTSHLLYSNSGSSRDWATD-LGINFSY 384

  Fly   376 TYELRPSGYSFWTGFRLPAAQIIPTGQETTDSLVEMIK 413
            |:|||.:|..   ||.|||.||.||.:||...::.:::
Frog   385 TFELRDTGAH---GFILPANQIRPTCEETMAGVMTIVE 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4017	NP_609309.1	Propep_M14	30..97	CDD:280416	9/39 (23%)
CG4017	NP_609309.1	M14_CP_A-B_like	119..415	CDD:199844	107/298 (36%)
cpo.1	XP_031748368.1	Propep_M14	36..105	CDD:396700	7/32 (22%)
cpo.1	XP_031748368.1	M14_CPO	124..421	CDD:349466	107/301 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	240	1.000	Domainoid score	I2216
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm9413
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.950