DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4017 and cpb2

DIOPT Version :9

Sequence 1:	NP_609309.1	Gene:	CG4017 / 34296	FlyBaseID:	FBgn0032143	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001018539.2	Gene:	cpb2 / 100000935	ZFINID:	ZDB-GENE-050522-259	Length:	424	Species:	Danio rerio

Alignment Length:	434	Identity:	142/434 - (32%)
Similarity:	222/434 - (51%)	Gaps:	54/434 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLLLLLSVNILIF---CLAERQRFDNYKVYRVSPVKANQLEGLRSLEANSEDAL--------VLN 56
            |:.|...:...||   ||.   :..:.:|..::......:|.:::|.:::|.||        :..
Zfish     4 LIQLAYFICFSIFLETCLC---KVKHDQVLAITVSSQEHVEKVQNLTSHNETALWQPASPNYITT 65

  Fly    57 N--LHLGPTDFLVAPDFDGTFLKLVK----DLDLSPELIDANAQTSLSLDIEPIADANRRSDDYS 115
            |  :||         ....|.::.||    :..::..::..|....:::.|.     |..||..|
Zfish    66 NSEVHL---------YIQSTSVQFVKEHLREHAITFRVLVENTAALVAMQIR-----NDTSDPRS 116

  Fly   116 ----WSEYHELNDTHRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHNDGRAEKQ---SIFL 173
                :..||.|.|.:.|:.....::.|:|.|.:.|.|.|.|.|..|:::   |:.|::   ::::
Zfish   117 GGVFYERYHSLEDIYYWINKTSREHSDMVKVILIGSSSEKRPLYVLKLS---GKREEEVNRAMWM 178

  Fly   174 EAGMHAREWIGPATATYFANELLS--SQQQEIMNLARSYVWYILPHANPDGYVYTHKTNRMWRKT 236
            :.|:||||||.||...:|.|..|:  :|..||..:......|||...|||||.||..|:|||||.
Zfish   179 DCGIHAREWIAPAFCMWFVNYALAFYNQNTEITEMLNKMDIYILTVMNPDGYKYTWTTDRMWRKN 243

  Fly   237 RSP-QDKNCVGTDPNRNWDFHWREVGASSDPCSESYAGPKAFSEPEVQTLSQFLKSVPEPMFMFL 300
            ||. :|..|.|.|.|||:|.:|...|||.|||..:|.|....||||.|.:::||:|..:.:.::|
Zfish   244 RSENKDSYCAGVDLNRNFDANWCTKGASDDPCDPTYCGQFPESEPETQAVAKFLRSHKDTVKLYL 308

  Fly   301 SLHSFSQLLLYPYGHTSALPENHRQLEQIFNTAVGAMKRRYGTRYTGGNVYDAIYPAAGSSMDWA 365
            |:||:||:||:||..:.....||.:|.::...|...::|.|...|..|:....||.|.|.|.|||
Zfish   309 SIHSYSQMLLFPYSCSYNEIPNHNELFELVKEASTKIRRYYRNNYKYGSGAKTIYLAPGGSDDWA 373

  Fly   366 YGVLNVKYSFTYELRPSGYSFWTGFRLPAAQIIPTGQETTDSLV 409
            |. |.:|||||:||:..|.   .||.||.: .||  |...::|:
Zfish   374 YD-LGIKYSFTFELQDRGQ---YGFLLPPS-FIP--QACNEALL 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4017	NP_609309.1	Propep_M14	30..97	CDD:280416	12/80 (15%)
CG4017	NP_609309.1	M14_CP_A-B_like	119..415	CDD:199844	118/297 (40%)
cpb2	NP_001018539.2	Propep_M14	32..98	CDD:280416	11/74 (15%)
cpb2	NP_001018539.2	M14_CPB2	120..420	CDD:199868	118/301 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593526
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm6559
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.680