Protein Alignment ppk18 and asic4b

DIOPT Version :10

• Sequence 1: NP_609308.3
• Gene: ppk18 / 34295
• FlyBaseID: FBgn0265001
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_999951.1
• Gene: asic4b / 407667
• ZFINID: ZDB-GENE-040513-6
• Length: 558
• Species: Danio rerio
• Alignment Length: 353
• Identity: 66/353 - (18%)
• Similarity: 115/353 - (32%)
• Gaps: 105/353 - (29%)

  Fly   227 TKRAEEDSEMRAVP---MVVFES-----NSILNSVQFVLQDTPKEDIT---------NTFHSNSA 274
            :::....||::..|   :.:|:.     ..:|.|..|..|:...||.:         .||:.|..
Zfish   148 SRKGHRPSELQYPPPNMLDIFQRTGHQLEDMLKSCNFSGQNCSSEDFSVVYTRYGKCYTFNGNKT 212

  Fly   275 F--------------QLIIFPQEDYATIQSTTLGEVLVDHYSIVEIPIQPMFFSSGDGVRGVPPH 325
            .              .::...|::|..|...|       :.:.:|..|:....|..:     ||:
Zfish   213 SPKRVRQGGTGNGLEMMLDIQQDEYLPIWRET-------NETTLEAGIRVQIHSQNE-----PPY 265

  Fly   326 IRRCYY------------PEEGMRLLNQSY----------------YSLDECLLVCRMKSMIDHC 362
            |.:..:            .|:.:..|.|.:                ||:..|.|.|....:...|
Zfish   266 IHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGNCRASSEPVIPGYDTYSVSACRLHCESTQVQREC 330

  Fly   363 GCVSPPLTGSSMDLDYCMLPDLPCLMRWKSIWYGYSDFAYLQNKEENLVQRQCEHCLPTCN---- 423
            .|....:.|   |.|.|....:.|:.:         ..|.||....:    .|. |...||
Zfish   331 NCRMVHMPG---DADICAPSKIKCVDK---------ALASLQKSTGD----SCP-CETPCNLTRY 378

  Fly   424 GVSMSITT-----NVAPLRRTYNSSGYFTGLLKGLTNERPLAIIKLFFKLRFAQATKSQMVSSWV 483
            |..:|:..     :...|.|.|..|..:.        .....|:.:||:....:..:.:......
Zfish   379 GKELSMVKIPSRGSARYLSRKYQKSEEYI--------RDNFLILDIFFEALNYETIEQKKAYDIA 435

  Fly   484 VLLNRFGGILSLMYGFSIVSYIEILYYL 511
            .||...||.:.|..|.||::.:|||.|:
Zfish   436 GLLGDIGGQMGLFIGASILTILEILDYI 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk18	NP_609308.3	ASC	16..510	CDD:459966	65/350 (19%)
asic4b	NP_999951.1	ENaC	54..497	CDD:273304	66/353 (19%)
		GAS motif, ion selectivity filter. /evidence=ECO:0000250|UniProtKB:P78348	450..452		1/1 (100%)