DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment und and MAP2A

DIOPT Version :9

Sequence 1:	NP_001260299.1	Gene:	und / 34294	FlyBaseID:	FBgn0283478	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_566013.1	Gene:	MAP2A / 819025	AraportID:	AT2G44180	Length:	441	Species:	Arabidopsis thaliana

Alignment Length:	447	Identity:	261/447 - (58%)
Similarity:	331/447 - (74%)	Gaps:	16/447 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 NVEAATPEIGEEVKKQKKPKPNNKKLRQEAAAKIASGEGGDEELTTNGDAKPATPAAQPAKKKGN 72
            |.|.||  :|:|..:.:....|..:|..:....:...|..::|...|.:.:....|....|||..
plant     5 NPEVAT--MGKENTEAESSNGNESQLSSDLTKSLDLAEVKEDEKDNNQEEEDGLKAEASTKKKKK 67

  Fly    73 KG----KKSG--QTDPPTIPIAKLYPDGNFPEGEIVEHPTPKDMPDDRTAKDRFTSEEKRALDRI 131
            |.    |||.  |||||:||:.:|:|.|:||:|||.::      .||...  |.||||||.::|:
plant    68 KSKSKKKKSSLQQTDPPSIPVLELFPSGDFPQGEIQQY------NDDNLW--RTTSEEKREMERL 124

  Fly   132 NTDIYQELRQAAEAHRQTRQYMQRYIKPGMTMIQICEELENTARRLIGENGLEAGLAFPTGCSLN 196
            ...||..||||||.|||.|:||:..:||||.||.:||.||||.|:||.||||:||:|||||||||
plant   125 QKPIYNSLRQAAEVHRQVRKYMRSILKPGMLMIDLCETLENTVRKLISENGLQAGIAFPTGCSLN 189

  Fly   197 HCAAHYTPNAGDPTVLQYDDVCKIDFGTHIKGRIIDCAFTLTFNNKYDKLLQAVKEATNTGIREA 261
            :.|||:|||:||.||||||||.|:||||||.|.|:|.|||:.||..:|.||.|.::||.|||:||
plant   190 NVAAHWTPNSGDKTVLQYDDVMKLDFGTHIDGHIVDSAFTVAFNPMFDPLLAASRDATYTGIKEA 254

  Fly   262 GIDVRLCDIGAAIQEVMESYEIELDGKTYPIKAIRNLNGHSISPYRIHAGKTVPIVKGGESTRME 326
            |:||||||:|||:||||||||:|::||.|.:|:|||||||||..|:|||.|:||.|:|||.|:||
plant   255 GVDVRLCDVGAAVQEVMESYEVEINGKVYQVKSIRNLNGHSIGRYQIHAEKSVPNVRGGEQTKME 319

  Fly   327 EDEFYAIETFGSTGRGLVHDDMDCSHYMKNFDLPFVPLRLQSSKQLLGTINKNFGTLAFCKRWLD 391
            |.|.||||||||||:|.|.:|::|||||||:|:..|||||..:||||.||||||.|||||:|:||
plant   320 EGELYAIETFGSTGKGYVREDLECSHYMKNYDVGHVPLRLPRAKQLLATINKNFSTLAFCRRYLD 384

  Fly   392 RAGATKYQMALKDLCDKGIVEAYPPLCDIKGCYTAQYEHTIMLRPTCKEVVSRGDDY 448
            |.|.|||.||||:|||.||:|..||:||:||.|.:|:||||:|||||||::|:||||
plant   385 RLGETKYLMALKNLCDSGIIEPCPPVCDVKGSYISQFEHTILLRPTCKEIISKGDDY 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
und	NP_001260299.1	PTZ00053	<79..448	CDD:240246	240/368 (65%)
MAP2A	NP_566013.1	PTZ00053	1..441	CDD:240246	259/445 (58%)
MAP2A	NP_566013.1	MetAP2	129..437	CDD:238521	211/307 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	457	1.000	Domainoid score	I95
eggNOG	1	0.900	-	-		E1_COG0024
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4981
Inparanoid	1	1.050	552	1.000	Inparanoid score	I254
OMA	1	1.010	-	-		QHG54020
OrthoDB	1	1.010	-	-		D601484at2759
OrthoFinder	1	1.000	-	-		FOG0003371
OrthoInspector	1	1.000	-	-		otm2550
orthoMCL	1	0.900	-	-		OOG6_100815
Panther	1	1.100	-	-	O	PTHR45777
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2266
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840