DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zf30C and CG7987

DIOPT Version :9

Sequence 1:	NP_477301.1	Gene:	zf30C / 34292	FlyBaseID:	FBgn0270924	Length:	777	Species:	Drosophila melanogaster
Sequence 2:	NP_650375.1	Gene:	CG7987 / 41768	FlyBaseID:	FBgn0038244	Length:	1283	Species:	Drosophila melanogaster

Alignment Length:	694	Identity:	148/694 - (21%)
Similarity:	238/694 - (34%)	Gaps:	163/694 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 DARFCHEEELT----QHAKDE------HGVTGAVAGQE-----------RKPFVCEKCGAEYKYQ 108
            ||:...||.:|    ||...|      ..:.|..:.||           .:|:.|:.|...::.:
  Fly    88 DAQVVTEEVITDDWVQHQGAERVEIAAEQIAGISSSQELLDMEQDEYTALRPYPCDFCSRRFRKK 152

  Fly   109 EAYRRHCRTKCGEEKLPREESRPMECKCCYTRFSSASNLSKHRRSRPDTCGQPEYDSPGSSDGMK 173
            .....|        .|..:..||..||.|..|||..:.|..|.::..:  .|...|:..::....
  Fly   153 ATLNNH--------MLAHQNDRPHLCKLCGARFSRRAELISHFKAHAE--AQDAADAEAAAAAAD 207

  Fly   174 KHKAFR-KKDRNRDSDDEDTTSE--------ESEDSDDDI------------------------P 205
            ...|.: :....|..||.....|        |.|::..::                        |
  Fly   208 SSSAIKFEHQTQRQLDDHYYEQEWPLFQHQQEQENAQQNVHQQHQIVEEGGIQLVASYPDTVAQP 272

  Fly   206 LA------SRLKTKLKQESQN----SDSG--DECPDFEPNNSEDDADASGF-QLPPPAMVKVEAF 257
            .|      ||||.  |:||..    ||..  |..|..||..::.....|.| .:.||........
  Fly   273 AAPSRGRISRLKP--KEESSQFIVISDKSVEDSRPYMEPEPAQPVVTTSEFIAVEPPPQPNFPVL 335

  Fly   258 D-EEDFEYQDASMYVKTESTDIFSNEKDKLLDVLLNEGDGLKPFESLKVEQGAGILDEIAAVPLV 321
            | .:.|..|...:....|.. :.|:.|:..:|         .|||..:.::
  Fly   336 DHSKPFVCQQCGLAFAREKA-LVSHTKNHRVD---------SPFECNQCQE-------------- 376

  Fly   322 EVAEEDVLELRGHQMEKPPGPRKRGRPPKEKIPVVKRKYRKRNAPRSPSPDDSSGTPKRVAKISK 386
              ...|...|:.||.                    ..::.:.|:...|:..:.||        |:
  Fly   377 --MFWDNSSLQEHQK--------------------THQFEESNSEYDPASAEESG--------SE 411

  Fly   387 KELKERLKMINKMEKSWKCPHCVKIYH----IRKPYEKHLRDDHKLNEAEMKEIFKDVDVHAKLD 447
            .|..|:|      ...:.|..|...:|    :|:..:.|.:...:.......::....||....|
  Fly   412 SEADEQL------YGEFYCNECGISFHRQDLLRRHAKMHCKPSDQAAVGSNSDVTAGGDVELAKD 470

  Fly   448 EEVFKCPICSKIYLVEKRLVTHMKVHGEDGKLTFKCPCYCNLFFATKEQATEHARAQHKELL--- 509
            .....|..|.|.:.....::.|.::|....  .||| ..|.:.|..::....|...:|...|
  Fly   471 SSGHCCNTCGKSFPSALEMLAHAEIHARFP--PFKC-VLCGISFYEEQAIKRHLHTRHPSELNAN 532

  Fly   510 YCEKCDKYMTGHDSLKNHERNFHSKKEPRSQQRNLICDKCGKKFTGRTSLSDHVRSDCGRLPLYG 574
            .|..|.|......:|..|..: ||:::..|      |.||||.|..:..|..|:.|...:..:
  Fly   533 SCVLCGKECRDRKALIKHAWD-HSREKCHS------CSKCGKNFHNKARLKRHMASHRDKSVV-- 588

  Fly   575 CSVCGKHLSTAGILKTHMLLHKADTP---YQCDKCGKTFKVKAQYKSHLKTRHTDYKPYKCHLCP 636
            |.||.:.......|..|...|...||   :.|.:|||||..::..:.|::. ||..:||.|..|.
  Fly   589 CEVCQEEFPDGRTLSNHRHSHSTTTPGKLFPCLECGKTFGSRSSQQIHVRI-HTGERPYGCRYCW 652

  Fly   637 KEYPYRESLLTHMTVHTGIKRFLCNNCGKRFTCISNLQAHRKVH 680
            |.:....:|..|..:|||.|.:.|:.|.:.|.....|:.|.:.|
  Fly   653 KAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSH 696

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zf30C	NP_477301.1	C2H2 Zn finger	33..53	CDD:275368
		C2H2 Zn finger	61..82	CDD:275368	8/26 (31%)
		C2H2 Zn finger	98..117	CDD:275368	3/18 (17%)
		C2H2 Zn finger	134..152	CDD:275368	8/17 (47%)
		C2H2 Zn finger	511..532	CDD:275370	5/20 (25%)
		COG5048	<523..>672	CDD:227381	45/151 (30%)
		C2H2 Zn finger	546..566	CDD:275368	8/19 (42%)
		C2H2 Zn finger	575..595	CDD:275368	5/19 (26%)
		C2H2 Zn finger	603..624	CDD:275368	7/20 (35%)
		C2H2 Zn finger	632..652	CDD:275368	5/19 (26%)
		C2H2 Zn finger	660..680	CDD:275368	5/19 (26%)
CG7987	NP_650375.1	C2H2 Zn finger	142..162	CDD:275368	4/27 (15%)
		C2H2 Zn finger	170..186	CDD:275368	7/15 (47%)
		COG5048	326..734	CDD:227381	96/444 (22%)
		C2H2 Zn finger	343..363	CDD:275368	4/20 (20%)
		C2H2 Zn finger	371..391	CDD:275368	4/55 (7%)
		C2H2 Zn finger	424..444	CDD:275368	4/19 (21%)
		C2H2 Zn finger	476..496	CDD:275368	4/19 (21%)
		C2H2 Zn finger	504..523	CDD:275368	4/19 (21%)
		C2H2 Zn finger	534..554	CDD:275370	5/20 (25%)
		C2H2 Zn finger	562..582	CDD:275370	8/19 (42%)
		C2H2 Zn finger	589..609	CDD:275368	5/19 (26%)
		C2H2 Zn finger	620..640	CDD:275368	7/20 (35%)
		C2H2 Zn finger	648..668	CDD:275368	5/19 (26%)
		zf-H2C2_2	661..685	CDD:290200	9/23 (39%)
		C2H2 Zn finger	676..696	CDD:275368	5/19 (26%)
		C2H2 Zn finger	709..726	CDD:275371
		Hph	921..>1017	CDD:290417
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100