DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zf30C and CG3281

DIOPT Version :9

Sequence 1:	NP_477301.1	Gene:	zf30C / 34292	FlyBaseID:	FBgn0270924	Length:	777	Species:	Drosophila melanogaster
Sequence 2:	NP_650132.1	Gene:	CG3281 / 41445	FlyBaseID:	FBgn0260741	Length:	538	Species:	Drosophila melanogaster

Alignment Length:	350	Identity:	88/350 - (25%)
Similarity:	144/350 - (41%)	Gaps:	61/350 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   418 YEKHLRDDH---------KLNEAEMKEIFKDVDVHAKLDEE---VFKCPICSKIYLVEKRLVTHM 470
            |....|||.         :.:|.|.:|:.:...:.::|:..   ::||.:|.:::...:.|..|.
  Fly   158 YASEDRDDEPEDSFQLKPRPDEIENRELSRPSQLGSRLNHSANFIYKCAVCPRVFAKSESLTRHF 222

  Fly   471 -KVHGEDGKLTFKCPCYCNLFFATKEQATEHARAQHKELLYCEKCDKYMTGHDSLKNHERNFH-- 532
             :.|    |||..        .|..:.|.|....   .||.||.|.:.....|:|:.|.:.||
  Fly   223 SQAH----KLTAD--------VAAMKLANESCGT---GLLTCEHCPRTFKRQDTLRRHMQAFHPD 272

  Fly   533 ------------SKKEPRSQQRNLICDKCGKKFTGRTSLSDHVRSDCGRLPLYGCSVCGKHLSTA 585
                        |.::..:::|:  |..||..|. .:||:.|:|...|..| |.|..|.|....:
  Fly   273 AIALEPEETTDNSARKRIAKRRD--CPHCGLSFP-VSSLTIHIRRHTGDNP-YKCDQCEKAFPRS 333

  Fly   586 GILKTHMLLHKADTPYQCDKCGKTFKVKAQYKSHLKTRHTDYKPYKCHLCPKEYPYRESLLTHMT 650
            ..|..||..|..:.|.:|..|.|.|..:.:...|::. ||..:||.|.:|.|.:.....|..||.
  Fly   334 QDLSLHMRQHTGERPSECKICSKKFISQNKLARHMRL-HTGQRPYSCKMCSKSFVQSNDLKIHMR 397

  Fly   651 VHTGIKRFLCNNCGKRFTCISNLQAHR-------------KVHADTCGQLPLNAKATQYMGVQRG 702
            .|||.:.:.|..||:.|.|.|:|..||             :|.|:......:||:..|.......
  Fly   398 RHTGERPYQCGVCGESFVCGSHLNIHRNRKGHLIAVIPGNEVEANFAADPYVNARVNQRRSEDIE 462

  Fly   703 KLLMGAKPEAGMEYEETKTLIAQDV 727
            ::.:...||..:: :..:.|...||
  Fly   463 RMRLQRIPENQLQ-QRLENLPKPDV 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zf30C	NP_477301.1	C2H2 Zn finger	33..53	CDD:275368
		C2H2 Zn finger	61..82	CDD:275368
		C2H2 Zn finger	98..117	CDD:275368
		C2H2 Zn finger	134..152	CDD:275368
		C2H2 Zn finger	511..532	CDD:275370	6/20 (30%)
		COG5048	<523..>672	CDD:227381	48/162 (30%)
		C2H2 Zn finger	546..566	CDD:275368	8/19 (42%)
		C2H2 Zn finger	575..595	CDD:275368	6/19 (32%)
		C2H2 Zn finger	603..624	CDD:275368	5/20 (25%)
		C2H2 Zn finger	632..652	CDD:275368	6/19 (32%)
		C2H2 Zn finger	660..680	CDD:275368	9/32 (28%)
CG3281	NP_650132.1	zf-AD	14..92	CDD:285071
		C2H2 Zn finger	205..226	CDD:275368	4/20 (20%)
		C2H2 Zn finger	249..266	CDD:275368	5/16 (31%)
		COG5048	<294..>391	CDD:227381	32/101 (32%)
		C2H2 Zn finger	296..315	CDD:275368	8/19 (42%)
		zf-H2C2_2	307..330	CDD:290200	10/23 (43%)
		C2H2 Zn finger	323..343	CDD:275368	6/19 (32%)
		zf-H2C2_2	335..358	CDD:290200	8/22 (36%)
		C2H2 Zn finger	351..371	CDD:275368	5/20 (25%)
		zf-H2C2_2	364..388	CDD:290200	8/24 (33%)
		C2H2 Zn finger	379..399	CDD:275368	6/19 (32%)
		zf-H2C2_2	391..416	CDD:290200	10/24 (42%)
		C2H2 Zn finger	407..424	CDD:275368	7/16 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010