DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment zf30C and CG1024

DIOPT Version :9

Sequence 1:	NP_477301.1	Gene:	zf30C / 34292	FlyBaseID:	FBgn0270924	Length:	777	Species:	Drosophila melanogaster
Sequence 2:	NP_001138014.2	Gene:	CG1024 / 40789	FlyBaseID:	FBgn0027514	Length:	543	Species:	Drosophila melanogaster

Alignment Length:	630	Identity:	117/630 - (18%)
Similarity:	212/630 - (33%)	Gaps:	200/630 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 CPVCNKALVSLAGYVKHVK-KH----QPPGGFECRHCDARFCHEEEL----TQHAKD-------- 80
            ||.|.||..:.|.:.:|:. ||    :....|.....|.|| ||.:|    .::|..
  Fly    30 CPECGKAFRTQAEWRQHLNTKHDYLKKTYSDFNFIQIDERF-HECQLCFKWVENAHKTIALLQYH 93

  Fly    81 -----EHGVTGAVAGQERKPFVCEKCGAEYKYQEAYRRHC------RTKCGEEKL---PREESRP 131
                 ||..|          :.|..|...|..:.|...|.      ..:..|.||   .|::::|
  Fly    94 YFMHLEHSET----------YRCVHCRMAYTRRRALNVHLLDTHMREIEKYENKLRQMKRQQAKP 148

  Fly   132 MECKCCYTRFSSASNLSKHRRSRPDTCGQPEYDSPGSSDGMKK---HKAFRKKDRNRDSDDEDTT 193
            .      |..:.|.|..|....:|.  |:|:    ||::..:.   .||....|.|.:.:....|
  Fly   149 T------TAAAPAGNAEKPMAVKPR--GRPK----GSTNRKQNDLLQKALMDIDLNTEMEKSPVT 201

  Fly   194 SEESEDSDDDIPLASRLKTKLKQESQNSDSGDECPDFEPNNSEDDADASGFQLPPPAMVKVEAFD 258
            :..:..::.. |:::..:..|          |.|    .|..||.......::.|....:::|..
  Fly   202 ALAAPVNEPK-PISNVSELNL----------DRC----LNAYEDIVRKEEKEVVPKYDDELDALC 251

  Fly   259 EEDFEYQDASMYVKTESTDIFSNEKDKLLDVLLNEGDGLKPFESLKVEQGAGILDEIAAVPLVEV 323
            :|.|:  |.....|.|     :||:.:..|..|.:|:                 .|:..:.:..:
  Fly   252 KEFFD--DGPSAGKGE-----ANEEQQQDDAHLQQGN-----------------QEVVIIEIDAL 292

  Fly   324 AEEDVLELRGHQMEKPPGPRKRGRPPKEKIPVVKRKYRKRNAPRSPSPDDSSGTPKRVAKISKKE 388
            .:|:|.:|: .:|:..|               :.:..::|....:||.|..:       ::|...
  Fly   293 GKEEVAQLK-KEMKSDP---------------ISQPTKRRRISTTPSRDSDT-------EMSTNG 334

  Fly   389 LKERLKMINKMEKSWKCPHCVKIYHIRKPYEKHLRDDHKLNEAEMKEIFKDVDVHAKLDEEVFKC 453
            |   .|:|     |:.||.|.|.......:..|:...|.. |..::..||.::...|.     .|
  Fly   335 L---TKLI-----SYLCPKCGKEIASMDGWRAHVFKKHDF-EHIIENSFKILESGRKA-----MC 385

  Fly   454 PICSKIY--LVEKRLVTHMKVHGEDGKLTFKCPCYCNLFFATKEQATEHARAQHKELLYCEKCDK 516
            ..|.::.  .|..:|..|               |:.:|              .::..|.|..||:
  Fly   386 LQCREVQPTTVRSQLQKH---------------CFKHL--------------PYRSYLKCTLCDR 421

  Fly   517 YMTGHDSLKNHERNFHSKKEPRSQQRNLICDK----CGKKFTGRTSLSDHVRS--DCGRLPLYGC 575
            ..|....:.||.|..|.::..|..:..|:...    .....:|:.:::|...|  |.|...:
  Fly   422 TKTSTSKILNHIRYNHQEELQRKNKTQLLIKPEPMWASPNKSGQAAMADDAGSEDDQGEQAV--- 483

  Fly   576 SVCGKHLSTAGILKTHMLLHKADTPYQCDKCGKTFKVKAQYKSHL 620
                                       |:.|.:.|:.|.:|:.|:
  Fly   484 ---------------------------CEHCDRVFRSKWRYERHI 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zf30C	NP_477301.1	C2H2 Zn finger	33..53	CDD:275368	7/20 (35%)
		C2H2 Zn finger	61..82	CDD:275368	7/37 (19%)
		C2H2 Zn finger	98..117	CDD:275368	5/24 (21%)
		C2H2 Zn finger	134..152	CDD:275368	4/17 (24%)
		C2H2 Zn finger	511..532	CDD:275370	7/20 (35%)
		COG5048	<523..>672	CDD:227381	17/104 (16%)
		C2H2 Zn finger	546..566	CDD:275368	3/25 (12%)
		C2H2 Zn finger	575..595	CDD:275368	0/19 (0%)
		C2H2 Zn finger	603..624	CDD:275368	6/18 (33%)
		C2H2 Zn finger	632..652	CDD:275368
		C2H2 Zn finger	660..680	CDD:275368
CG1024	NP_001138014.2	C2H2 Zn finger	30..51	CDD:275368	7/20 (35%)
		C2H2 Zn finger	73..100	CDD:275368	2/26 (8%)
		C2H2 Zn finger	106..123	CDD:275368	4/16 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100