DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment zf30C and CG31612

DIOPT Version :9

Sequence 1:	NP_477301.1	Gene:	zf30C / 34292	FlyBaseID:	FBgn0270924	Length:	777	Species:	Drosophila melanogaster
Sequence 2:	NP_001163042.1	Gene:	CG31612 / 35427	FlyBaseID:	FBgn0051612	Length:	987	Species:	Drosophila melanogaster

Alignment Length:	676	Identity:	140/676 - (20%)
Similarity:	223/676 - (32%)	Gaps:	237/676 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 ECRHCDARFCHEEELTQHAKDEH---GVTGAVAGQERKPFVCEKCGAEYKYQEAYRRHCRTKCGE 121
            :|..|...|.:..:|.||:..||   .:||..|.:.:..|.|..||:..|.:.|.:||.:.|
  Fly   491 QCSRCGMEFLYNIQLRQHSITEHPGLALTGTAADEYQSRFRCNLCGSSQKSRLALQRHKKHK--- 552

  Fly   122 EKLPREESRPMECKCCYTRFSSASNLSKHR-------RSRPDT-CGQPEYDSPGSSDGMKKHKAF 178
            ..|.|     ..|..|...|.::.:..:||       ::||.| ..|||
  Fly   553 HHLAR-----YFCAICRLEFDNSLDARRHRSLVIHKQKARPQTSIPQPE---------------- 596

  Fly   179 RKKDRNRDSDDEDTTSEESEDSDDDIPLASRLKTKLKQESQNSDSGDECPDFEPNNSEDDADASG 243
                    ::.|....|..|::....|           ..:::|...:|     :||....
  Fly   597 --------NEIEHMLREVLEETVPSPP-----------AKRSADVNAKC-----SNSRKTI---- 633

  Fly   244 FQLPPPAMVKVEAFDEEDFEYQDASMYVKTESTDIFSNEKDKLLDVLLNEGDGLKPFESLKVEQG 308
                                  ::|..:.....::.|::....|...::       |||.:.
  Fly   634 ----------------------ESSQRLAQHQAEVHSSDNHLCLSCGIS-------FESAQA--- 666

  Fly   309 AGILDEIAAVPLVEVAEEDVLELRGHQMEKPPGPRKRGRPPKEKIPVVKRKYRKRNAPRSPSPDD 373
                                  |..|                               .||..|..
  Fly   667 ----------------------LGRH-------------------------------TRSCQPLA 678

  Fly   374 SSGTPKRVAKISKKELKERLKMINKMEKSWKCPHCVKIYHIRKPYEKHLRDDHKLNEAEMKEIFK 438
            |:.||..:::..||.:             :.|..|    ..:..||..| ..|::.......|.|
  Fly   679 STSTPADLSQAQKKSM-------------YSCDQC----RFQSQYESDL-VYHRIFHTRSGTIGK 725

  Fly   439 DVDVHAKLDEEVFKCPICSKIYLVEKRLVTHMKVHGEDGKLTFKCPCYCNLFFATKEQ-----AT 498
            :         ||.:||:|.|.: .:..|..|::.|..: |: |:| ..|...||.:..     .|
  Fly   726 N---------EVLQCPLCPKNF-KKHSLRAHLRNHTNE-KI-FEC-TECLQKFARRHNLKNHVIT 777

  Fly   499 EHARA--------------QHKELLYCEKCDKYMTGHDSLKNHERNFHSKKEPRSQQRNLICDKC 549
            :||:.              |.|....|..|.|.:....|||.||.: |||    :.:||.:|...
  Fly   778 KHAKVGDKEKKKYAAKDVEQSKPKYQCGTCGKLLAKKYSLKLHEIS-HSK----AVERNYLCHFA 837

  Fly   550 GKKFTGRT--SLSDHVRS------DCGRLPLYGCSVCGK-------HLSTAGILKTHMLLHKADT 599
            ...:.|||  ||..|:.|      .|.|:   .||..||       ||.:|     |......:.
  Fly   838 DCSYAGRTPESLKTHLVSHSQENHKCARI---NCSYVGKSELHLKRHLKSA-----HSTEKNGEE 894

  Fly   600 PYQCDKCGKTFKVKAQYKSHLKTRHTDYKPYKCHLCPKEYPYRESLLTHMT---VHTGIKRFLCN 661
            .:.||:|....::|...:.| ..||:..||::|..|..:....::|..|:.   .|.|:..:.|.
  Fly   895 WFSCDQCDFRARIKGHLRRH-SLRHSGQKPHQCPHCDFQCSTIDNLRKHIIKTGKHPGMFIYHCA 958

  Fly   662 NC-----GKRFTCIS--NLQAHRKVH 680
            .|     |:.|...|  ..|.|.|.|
  Fly   959 KCSDEEAGEIFKSNSYKEYQHHLKTH 984

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zf30C	NP_477301.1	C2H2 Zn finger	33..53	CDD:275368
		C2H2 Zn finger	61..82	CDD:275368	6/20 (30%)
		C2H2 Zn finger	98..117	CDD:275368	7/18 (39%)
		C2H2 Zn finger	134..152	CDD:275368	5/24 (21%)
		C2H2 Zn finger	511..532	CDD:275370	8/20 (40%)
		COG5048	<523..>672	CDD:227381	48/173 (28%)
		C2H2 Zn finger	546..566	CDD:275368	8/27 (30%)
		C2H2 Zn finger	575..595	CDD:275368	8/26 (31%)
		C2H2 Zn finger	603..624	CDD:275368	5/20 (25%)
		C2H2 Zn finger	632..652	CDD:275368	4/22 (18%)
		C2H2 Zn finger	660..680	CDD:275368	8/26 (31%)
CG31612	NP_001163042.1	C2H2 Zn finger	697..717	CDD:275368	6/24 (25%)
		C2H2 Zn finger	731..750	CDD:275368	6/19 (32%)
		C2H2 Zn finger	758..779	CDD:275368	5/21 (24%)
		C2H2 Zn finger	804..824	CDD:275368	8/20 (40%)
		C2H2 Zn finger	834..856	CDD:275368	7/21 (33%)
		C2H2 Zn finger	898..918	CDD:275368	5/20 (25%)
		zf-H2C2_2	910..935	CDD:290200	7/25 (28%)
		C2H2 Zn finger	926..945	CDD:275368	4/18 (22%)
		C2H2 Zn finger	957..984	CDD:275368	8/26 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100