DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zf30C and CG1529

DIOPT Version :9

Sequence 1:	NP_477301.1	Gene:	zf30C / 34292	FlyBaseID:	FBgn0270924	Length:	777	Species:	Drosophila melanogaster
Sequence 2:	NP_001138223.2	Gene:	CG1529 / 33077	FlyBaseID:	FBgn0031144	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	361	Identity:	73/361 - (20%)
Similarity:	143/361 - (39%)	Gaps:	112/361 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   376 GTPKRVAKISKK------ELKERLKMINKMEKSWKCPHCVKIYHIR-KPYEKHLRDDHKLNEAEM 433
            |.|..:..:...      ||::..:..::....|: |..:.:..:: :|.::.|:::|:.||.|:
  Fly    49 GFPTEICNLCHNAVVYFDELRQVARESSQKLIGWQ-PVDIAVDRVKEEPPDEGLKENHEENEHEL 112

  Fly   434 KEIF------KDVDVHAKL-----------DEEV----------------------FKCPICSKI 459
            :|..      :.||:..|.           |||.                      ..|..|
  Fly   113 EEEHEKQADGQQVDLSKKQEDQKKILDDREDEEYPDEYENSQQQLSQGTGSKRRAGLACDQC--- 174

  Fly   460 YLVEKRLVTHMKVHGEDGKLTFKCPCYCNLFFATKEQATEHARAQHK---ELLYCEKCDKYMTGH 521
                             ||..:|.|           ....|.|:.|:   :...|..|||..|.:
  Fly   175 -----------------GKQVYKLP-----------YLEAHIRSVHQGYSKPFLCRSCDKSFTRY 211

  Fly   522 DSLKNHERNFHSKKEPRSQQ-RNLICDKCGKKFTGRTSLSDHVRSDCGRLPLYGCSVCGKHLSTA 585
            :.|::|.||.|.:.|...|: |:|||:.|.::::.:.:|.:|::....|
  Fly   212 EQLRSHMRNAHPQLEQLQQELRDLICELCNRQYSTKNALGEHLKRHAQR---------------- 260

  Fly   586 GILKTHMLLHKADTPYQCDKCGKTFKVKAQYKSHLKTRHTDYKPYKCHLCPKEYPYRESLLTHM- 649
               |.|:          |:.||.....:.:..:||:|.:..::.:||..||:.:.::.::..|:
  Fly   261 ---KEHV----------CEHCGVAKVTRTELLTHLRTHNPTWERFKCEQCPQLFRHKSAISRHVR 312

  Fly   650 TVHTGIKRFLCNNCGKRFTCISNLQAHRKVHADTCG 685
            .||.|.:||.|.:|.|:|...::...|.::|.::.|
  Fly   313 VVHEGQRRFQCGHCEKKFGTHASQVRHERLHTESTG 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zf30C	NP_477301.1	C2H2 Zn finger	33..53	CDD:275368
		C2H2 Zn finger	61..82	CDD:275368
		C2H2 Zn finger	98..117	CDD:275368
		C2H2 Zn finger	134..152	CDD:275368
		C2H2 Zn finger	511..532	CDD:275370	9/20 (45%)
		COG5048	<523..>672	CDD:227381	37/150 (25%)
		C2H2 Zn finger	546..566	CDD:275368	4/19 (21%)
		C2H2 Zn finger	575..595	CDD:275368	2/19 (11%)
		C2H2 Zn finger	603..624	CDD:275368	6/20 (30%)
		C2H2 Zn finger	632..652	CDD:275368	4/20 (20%)
		C2H2 Zn finger	660..680	CDD:275368	5/19 (26%)
CG1529	NP_001138223.2	zf-AD	11..79	CDD:285071	4/29 (14%)
		C2H2 Zn finger	171..192	CDD:275368	8/51 (16%)
		zf-C2H2_2	201..>257	CDD:289522	19/55 (35%)
		C2H2 Zn finger	201..222	CDD:275368	9/20 (45%)
		C2H2 Zn finger	237..257	CDD:275368	4/19 (21%)
		C2H2 Zn finger	265..285	CDD:275368	5/19 (26%)
		zf-C2H2_8	268..349	CDD:292531	22/81 (27%)
		C2H2 Zn finger	294..315	CDD:275368	4/20 (20%)
		C2H2 Zn finger	323..343	CDD:275368	5/19 (26%)
		C2H2 Zn finger	360..380	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100