DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zf30C and klf-2

DIOPT Version :9

Sequence 1:	NP_477301.1	Gene:	zf30C / 34292	FlyBaseID:	FBgn0270924	Length:	777	Species:	Drosophila melanogaster
Sequence 2:	NP_507995.2	Gene:	klf-2 / 186179	WormBaseID:	WBGene00009998	Length:	299	Species:	Caenorhabditis elegans

Alignment Length:	176	Identity:	39/176 - (22%)
Similarity:	64/176 - (36%)	Gaps:	60/176 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   518 MTGHDS------LKNHERNFH--SKKEPR---SQQRNLICDKCGKKFTGRTSLSDHVRSDCGRLP 571
            ::|.|.      ||:..|.:|  |.::|:   |::|:                    ::...||.
Worm   152 LSGKDEEDPRIPLKDRGRVYHPQSTEKPKKVPSKRRD--------------------KATLDRLR 196

  Fly   572 LYGC--SVCGKHLSTAGILKTHMLLHKADTPYQCDKCGKTFKVKAQYKSHLKTRHTDYKPYKCHL 634
            ::.|  ..|||..:.:..|..|..:|..:.||.|:..|
Worm   197 VHKCFYQGCGKVYTKSSHLTAHERVHSGEKPYPCEWPG--------------------------- 234

  Fly   635 CPKEYPYRESLLTHMTVHTGIKRFLCNNCGKRFTCISNLQAHRKVH 680
            |...:...:.|..|...|||.|.|.|..|.::|:...:||.|.|.|
Worm   235 CSWRFARSDELTRHYRKHTGAKPFACKECSRKFSRSDHLQLHMKRH 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zf30C	NP_477301.1	C2H2 Zn finger	33..53	CDD:275368
		C2H2 Zn finger	61..82	CDD:275368
		C2H2 Zn finger	98..117	CDD:275368
		C2H2 Zn finger	134..152	CDD:275368
		C2H2 Zn finger	511..532	CDD:275370	5/19 (26%)
		COG5048	<523..>672	CDD:227381	32/161 (20%)
		C2H2 Zn finger	546..566	CDD:275368	0/19 (0%)
		C2H2 Zn finger	575..595	CDD:275368	6/21 (29%)
		C2H2 Zn finger	603..624	CDD:275368	2/20 (10%)
		C2H2 Zn finger	632..652	CDD:275368	3/19 (16%)
		C2H2 Zn finger	660..680	CDD:275368	7/19 (37%)
klf-2	NP_507995.2	C2H2 Zn finger	205..222	CDD:275368	5/16 (31%)
		C2H2 Zn finger	230..252	CDD:275368	5/48 (10%)
		zf-H2C2_2	244..269	CDD:290200	10/24 (42%)
		C2H2 Zn finger	260..280	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BRQ6
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900