DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment zf30C and ztf-16

DIOPT Version :9

Sequence 1:	NP_477301.1	Gene:	zf30C / 34292	FlyBaseID:	FBgn0270924	Length:	777	Species:	Drosophila melanogaster
Sequence 2:	NP_001024851.1	Gene:	ztf-16 / 180756	WormBaseID:	WBGene00019960	Length:	480	Species:	Caenorhabditis elegans

Alignment Length:	445	Identity:	87/445 - (19%)
Similarity:	147/445 - (33%)	Gaps:	147/445 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 CPVCNKALVSLAGYVKHVKKHQPPGGFECRHCDARFCHEEELTQHAKDEHGVTGAVAGQERKPFV 97
            |.:|.......|...:|..:|.....:|||.|..||..::::.:|:. .|..||.       .|.
Worm   135 CDICKMQFSQKANMHRHRMRHSGVKPYECRFCKKRFFRKDQMQEHSM-THIKTGF-------GFD 191

  Fly    98 C--EKCGAEYKYQEAYRRHCRTKCGEEKLPREESRPMECKCCYTRFSSASNLSKHRRSRPDTCGQ 160
            |  .:|..::....|.|.|.     ||......:.|..||.|...|:::..|..|.::|.|
Worm   192 CPVSQCNMQFSQHNALRAHL-----EETHTISSTNPASCKRCNLMFANSRRLLLHFQTRHD---- 247

  Fly   161 PEYDSPGSSDGMKKHKAFRKKDRNRDSDDEDTTSEESEDSDDDIPLASRLKTKLKQESQNSDSGD 225
               ||  .|...|::...|||..|.::...|..         ::.:..:|:..:|.|
Worm   248 ---DS--ESSPKKENTPKRKKLSNGNALPMDPA---------NMSITEQLQRMVKSE-------- 290

  Fly   226 ECPDFEPNNSE--DDADASGFQLPPPAMVKVEAFDEEDFEYQDASMYVKTESTDIFSNEKDKLLD 288
                |.|.|::  |::.:|.|...||:                            |......:|.
Worm   291 ----FSPPNTDTSDNSTSSEFDKIPPS----------------------------FPMANPDILL 323

  Fly   289 VLLNEGDGLKPFESLKVEQGAGI---LDEIAAVPL---------VEVAEEDVLELRGHQME---- 337
            :.||:.:....|       |..|   :..|..:||         ..:.::|.::|...|..
Worm   324 MCLNQMNQFNGF-------GENIPRPMLNIPNIPLPALHNIPAVAAIVKQDQVQLWSEQTSSSVS 381

  Fly   338 -KPPGPRKRGRPPKEKIPVVKRKYRKRNAPRSPSPDDSSGTPKRVAKISKKELKERLKMINKMEK 401
             ..|.|.::...|    |..:.........:||:|:              ||.:|.:
Worm   382 VSAPSPSEQSHSP----PANESSLSLTEKEKSPTPE--------------KEDEENV-------- 420

  Fly   402 SWKCPHCVKIYHIRKPYEKHLRDDHKLNEAEMKEIFKDVDVHAKLDEEVFKCPIC 456
              :|.||..:::....|..|            |.:..|.|        .|||.:|
Worm   421 --ECCHCGMMFYDNTMYLLH------------KSLHSDGD--------PFKCALC 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zf30C	NP_477301.1	C2H2 Zn finger	33..53	CDD:275368	4/19 (21%)
		C2H2 Zn finger	61..82	CDD:275368	6/20 (30%)
		C2H2 Zn finger	98..117	CDD:275368	5/20 (25%)
		C2H2 Zn finger	134..152	CDD:275368	6/17 (35%)
		C2H2 Zn finger	511..532	CDD:275370
		COG5048	<523..>672	CDD:227381
		C2H2 Zn finger	546..566	CDD:275368
		C2H2 Zn finger	575..595	CDD:275368
		C2H2 Zn finger	603..624	CDD:275368
		C2H2 Zn finger	632..652	CDD:275368
		C2H2 Zn finger	660..680	CDD:275368
ztf-16	NP_001024851.1	C2H2 Zn finger	105..125	CDD:275368
		C2H2 Zn finger	135..155	CDD:275368	4/19 (21%)
		C2H2 Zn finger	163..183	CDD:275368	6/20 (30%)
		C2H2 Zn finger	225..246	CDD:275368	6/20 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910