Protein Alignment Cyp4e3 and DIT2

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_010690.1
• Gene: DIT2 / 852011
• SGDID: S000002810
• Length: 489
• Species: Saccharomyces cerevisiae
• Alignment Length: 455
• Identity: 106/455 - (23%)
• Similarity: 185/455 - (40%)
• Gaps: 86/455 - (18%)

  Fly    66 YGKDNFLFWIGYSSHIVMTNPKQLEYILNSQQLI-----QKSTIYDLLHPWLGHGLLTSFGSKWH 125
            ||...|.|  |...:|:::..:.|..|...:...     ||...|..|..:.|..:::::|:.|.
Yeast    66 YGAVKFFF--GSRWNILVSRSEYLAQIFKDEDTFAKSGNQKKIPYSALAAYTGDNVISAYGAVWR 128

  Fly   126 KHRKMITPSFHFNILQDFHEVMNENSAKFMTQL--KKASAGDTIIDFQEHANYLTLDVICDTAMG 188
            .:|..:|     |.||.|.:.....:||.:..|  .:...|.|.|.....:..:.||.|...|:|
Yeast   129 NYRNAVT-----NGLQHFDDAPIFKNAKILCTLIKNRLLEGQTSIPMGPLSQRMALDNISQVALG 188

  Fly   189 VPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKTLKTLQDFTYDIIEK 253
            ....|:....:    ||.:....|..:.||||..:.....:.| ..:.:|..|.:..|. :::.|
Yeast   189 FDFGALTHEKN----AFHEHLIRIKKQIFHPFFLTFPFLDVLP-IPSRKKAFKDVVSFR-ELLVK 247

  Fly   254 RVY-ALQNGGSKEDHDPSLPRKKMAFLDTLL---SSTIDGRPLTRQEIYEEVSTFMFEGHDTTTS 314
            ||. .|.|....|       :...|..|.:.   :..||.:.||     :.:...:..||:....
Yeast   248 RVQDELVNNYKFE-------QTTFAASDLIRAHNNEIIDYKQLT-----DNIVIILVAGHENPQL 300

  Fly   315 GVSFSVYLLSRHP-DVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSV-PFI 377
            ..:.|:|||:::. :.|.||.:|        :|.....:.:|.:..|:.|:.|..|:||.: ..|
Yeast   301 LFNSSLYLLAKYSNEWQEKLRKE--------VNGITDPKGLADLPLLNAFLFEVVRMYPPLSTII 357

  Fly   378 GRYCDKDYDINGSIV-PKGTTLNLALILLGYNDRIFKDPH----------HFRPERFEEEKPAPF 431
            .|...|...:...|| |||       :.:|||:  |...|          .|:|||:..:    .
Yeast   358 NRCTTKTCKLGAEIVIPKG-------VYVGYNN--FGTSHDPKTWGTTADDFKPERWGSD----I 409

  Fly   432 EYL--------------PFSAGPRNCIGQKFALLELKTVISKVVRSF--EVLPAVDELVSTDGRL 480
            |.:              .|..|.|.|:|:|.||.|::..::::::.|  .:.|..:|.::..|.|
Yeast   410 ETIRKNWRMAKNRCAVTGFHGGRRACLGEKLALTEMRISLAEMLKQFRWSLDPEWEEKLTPAGPL 474

  Fly   481  480
            Yeast   475  474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	104/453 (23%)
DIT2	NP_010690.1	CYP56-like	65..485	CDD:410693	106/455 (23%)