DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4e3 and CYP94D1

DIOPT Version :9

Sequence 1:	NP_523527.1	Gene:	Cyp4e3 / 34291	FlyBaseID:	FBgn0015035	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_174713.1	Gene:	CYP94D1 / 840356	AraportID:	AT1G34540	Length:	498	Species:	Arabidopsis thaliana

Alignment Length:	570	Identity:	148/570 - (25%)
Similarity:	240/570 - (42%)	Gaps:	124/570 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LAVLALLVLPL-ITLVYFERKASQRRQLLKEFNGPTPVPILGNANRIGKNPAEILSTFFDWWYD- 65
            |..:.||..|: |..::|.:|:|      .|| |....||:|:...:..|    ...|.||..:
plant     4 LIFIFLLCFPISIFFIFFTKKSS------SEF-GFKSYPIVGSFPGLVNN----RHRFLDWTVET 57

  Fly    66 ---YGKDNFLFWIGYSSHIVMT-NPKQLEYILNS--QQLIQKSTIYDLLHPWLGHGLLTSFGSKW 124
               ......:|.......::|| ||..:||:|.:  :...:......:|..:||||:..|.|..|
plant    58 LSRCPTQTAIFRRPGKQQLIMTANPSNVEYMLKTKFESFPKGQQFTSVLEDFLGHGIFNSDGDMW 122

  Fly   125 HKHRKMITPSFHFNILQDF--HEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVIC---- 183
            .|.||..:..|....|:||  ..|..|.:.:.:..|.:|:....:||.|:.......|.||
plant   123 WKQRKTASYEFSTKSLRDFVMSNVTVEINTRLVPVLVEAATTGKLIDLQDILERFAFDNICKLAF 187

  Fly   184 ---------DTAMGVP-INAMEQRDSSIVQAFRDMC---------YNINMRAFHPFKRSNRVFSL 229
                     |.|:||. :.|.|...:.|.|.||.:.         .||.         |.||.
plant   188 NVDCACLGHDGAVGVNFMRAFETAATIISQRFRSVASCAWRIKKKLNIG---------SERVL-- 241

  Fly   230 TPEFSAYQKTLKTLQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLLSSTIDGRPLTR 294
                   ::::.|:..|..:|:..|:    :.|...||.           :.|||..|....:..
plant   242 -------RESIATVHKFADEIVRNRI----DQGRSSDHK-----------EDLLSRFISKEEMNS 284

  Fly   295 QEIYEE-VSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEV---MGHDMNRSVSFQEIA 355
            .||..: |.:|:..|.|||:|.:|:..:|||.||:|:.|:.:|...:   .|..:.....|:.:.
plant   285 PEILRDIVISFILAGRDTTSSALSWFFWLLSMHPEVEDKILQELNSIRARTGKRIGEVYGFEHLK 349

  Fly   356 KMKYLDLFIKEAQRVYPSVPFIGRYCDKDYDI-NGSIVPKGTTLNLALILLGYNDRIF-KDPHHF 418
            .|.||...|.|:.|:||.||...:.|.:|..: :|:.|.||..:...:..:|..:.|: ||...|
plant   350 MMNYLHAAITESLRLYPPVPVDIKSCAEDNVLPDGTFVGKGWAITYNIFAMGRMESIWGKDCDRF 414

  Fly   419 RPER--------FEEEKPAPFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEV-LPAVDELV 474
            .|||        |..|.|:.|.  .|.||||.|:|:..|.:::|::::.|:..|.| :|
plant   415 DPERWIDETNGCFRGEDPSKFP--AFHAGPRMCVGKDMAYIQMKSIVAAVLERFVVEVP------ 471

  Fly   475 STDGRLNTYLGLAPDEKLKREAGRHKYDPILSAVLTLKSDNGLHLRLRER 524
                                  |:.:.:.:||  :||:...||..|::||
plant   472 ----------------------GKERPEILLS--MTLRIKGGLFARVQER 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	p450	35..468	CDD:278495	127/479 (27%)
CYP94D1	NP_174713.1	CYP86A	64..490	CDD:410687	125/490 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920