DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4e3 and CYP97A3

DIOPT Version :9

Sequence 1:	NP_523527.1	Gene:	Cyp4e3 / 34291	FlyBaseID:	FBgn0015035	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_564384.1	Gene:	CYP97A3 / 840067	AraportID:	AT1G31800	Length:	595	Species:	Arabidopsis thaliana

Alignment Length:	503	Identity:	122/503 - (24%)
Similarity:	224/503 - (44%)	Gaps:	74/503 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 PVPILGNANRIGKNPAEILSTFFDWW---YDYGK-----------DNFLFWI------------- 75
            |..:....::|| .|:.:|...|||.   .||.|           .|..|:|
plant    80 PSTVKNGLSKIG-IPSNVLDFMFDWTGSDQDYPKVPEAKGSIQAVRNEAFFIPLYELFLTYGGIF 143

  Fly    76 ----GYSSHIVMTNPKQLEYIL-NSQQLIQKSTIYDLLHPWLGHGLLTSFGSKWHKHRKMITPSF 135
                |..|.:::::|...::|| ::.:...|..:.::|...:|.||:.:.|..|.:.|:.|.|:.
plant   144 RLTFGPKSFLIVSDPSIAKHILKDNAKAYSKGILAEILDFVMGKGLIPADGEIWRRRRRAIVPAL 208

  Fly   136 HFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVICDTAMGVPINAMEQRDSS 200
            |...:.....:..|.|.:...:|..|:.....::.:...:.||||:|.........::: ..|:.
plant   209 HQKYVAAMISLFGEASDRLCQKLDAAALKGEEVEMESLFSRLTLDIIGKAVFNYDFDSL-TNDTG 272

  Fly   201 IVQAFRDMCYNINMRAFHPFKRSNRVF------SLTPEFSAYQKTLKTLQDFTYDIIE--KRVYA 257
            :::|...:......|:..|..    |:      .::|.......:||.:.|...|:|.  ||:..
plant   273 VIEAVYTVLREAEDRSVSPIP----VWDIPIWKDISPRQRKVATSLKLINDTLDDLIATCKRMVE 333

  Fly   258 LQNGGSKEDH----DPSLPRKKMAFLDTLLSSTIDGRPLTRQEIYEEVSTFMFEGHDTTTSGVSF 318
            .:.....|::    |||:       |..||:|   |..::.:::.:::.|.:..||:|:.:.:::
plant   334 EEELQFHEEYMNERDPSI-------LHFLLAS---GDDVSSKQLRDDLMTMLIAGHETSAAVLTW 388

  Fly   319 SVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCDK 383
            :.|||:..|.|..||..|...|:|   :|..:.|::.|:||....:.|:.|:||..|.:.|. ..
plant   389 TFYLLTTEPSVVAKLQEEVDSVIG---DRFPTIQDMKKLKYTTRVMNESLRLYPQPPVLIRR-SI 449

  Fly   384 DYDINGSI-VPKGTTLNLALILLGYNDRIFKDPHHFRPERFEEEKPAP------FEYLPFSAGPR 441
            |.||.|.. :.:|..:.:::..|..:...:.|...|.|||:..:.|.|      |.||||..|||
plant   450 DNDILGEYPIKRGEDIFISVWNLHRSPLHWDDAEKFNPERWPLDGPNPNETNQNFSYLPFGGGPR 514

  Fly   442 NCIGQKFALLELKTVISKVVR--SFEVLPAVDELVSTDG-RLNTYLGL 486
            .|||..||..|....|:.::|  :|::.|....:..|.| .::|..||
plant   515 KCIGDMFASFENVVAIAMLIRRFNFQIAPGAPPVKMTTGATIHTTEGL 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	p450	35..468	CDD:278495	116/482 (24%)
CYP97A3	NP_564384.1	PLN02738	1..595	CDD:215393	122/503 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.920