DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4e3 and CYP96A4

DIOPT Version :9

Sequence 1:	NP_523527.1	Gene:	Cyp4e3 / 34291	FlyBaseID:	FBgn0015035	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_200045.1	Gene:	CYP96A4 / 835308	AraportID:	AT5G52320	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	472	Identity:	100/472 - (21%)
Similarity:	190/472 - (40%)	Gaps:	78/472 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 WIGYSSHIVMTNPKQLEYILNSQQL-IQKSTIYDLLHPWLGHGLLTSFGSKWHKHRKMITPSFHF 137
            |:..:..::..:|..::|||:|..: ..|...::.:..:||.|:.......|...|......|..
plant    74 WLSGTDILLTVDPVNIQYILSSNFVNYPKGKKFNKIFEFLGDGIFNVDSGLWEDMRNSSHAIFSH 138

  Fly   138 NILQDFHEVMNENSAKFMTQ-----LKKASAGDTIIDFQEHANYLTLDVICDTAMGVPINAMEQR 197
               |||.......|...::|     |..|.....::|.|:.......|.......|....::...
plant   139 ---QDFQSFSVSTSVSKLSQGLVPILDNAVEKHILVDLQDLFQRFLFDTSSTLMAGYDPKSLSVE 200

  Fly   198 DSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSA-----YQKTLKTLQDFTYDIIEKRVYA 257
            ...:  .|.|....:....|:...:...::|:......     .::.|.........||..:...
plant   201 MPKV--EFADAMDGVADAMFYRHLKPAFLWSIQSWIGVGIEKKMRRGLDVFDQMLGKIISAKREE 263

  Fly   258 LQNGGSKEDHDPSLPRKKMAFLDTL-LSSTIDG------RPLTRQEIYEEVSTFMFEGHDTTTSG 315
            ::|.|.   ||     .|...:|.| ...|||.      :|...:.|.:.:...:....|||:|.
plant   264 IKNHGI---HD-----SKGEAMDVLTYYMTIDTTKYKHLKPSNDKFIRDTILGLVIAARDTTSSA 320

  Fly   316 VSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSV-SFQ--EIAKMKYLDLFIKEAQRVYPSVPFI 377
            :::..:|||::|:...|:.:|        :|:.: .|.  ::.|:.|||..:.|..|:||||||.
plant   321 LTWFFWLLSKNPEAMTKIRQE--------INKKMPKFDPADLDKLVYLDGAVCETLRLYPSVPFN 377

  Fly   378 GRYCDK-DYDINGSIVPKGTTLNLALILLGYNDRIF-KDPHHFRPERFEEE-----KPAPFEYLP 435
            .:...| |...:|..|.|...:.:.:..||....:: .|...|||||:..:     :.:.:::|.
plant   378 HKSPAKPDVLPSGHKVDKNWRVVIPIYSLGRMKSVWGDDAEDFRPERWISDSGMLRQESSYKFLA 442

  Fly   436 FSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKREAGRHK 500
            |:||||.|:|::...|::|||..:::|::::                           :....||
plant   443 FNAGPRTCLGKRLTFLQMKTVAVEIIRNYDI---------------------------KVVEGHK 480

  Fly   501 YDPILSAVLTLKSDNGL 517
            ..|:.|.:|.::  :||
plant   481 PKPVPSVLLRMQ--HGL 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	p450	35..468	CDD:278495	93/421 (22%)
CYP96A4	NP_200045.1	p450	1..501	CDD:416425	100/472 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H111093
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920