DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4e3 and AT5G08250

DIOPT Version :9

Sequence 1:	NP_523527.1	Gene:	Cyp4e3 / 34291	FlyBaseID:	FBgn0015035	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_001330676.1	Gene:	AT5G08250 / 830721	AraportID:	AT5G08250	Length:	550	Species:	Arabidopsis thaliana

Alignment Length:	548	Identity:	124/548 - (22%)
Similarity:	232/548 - (42%)	Gaps:	119/548 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 KEFNGPTPVPILGNANRIGKNPAEILSTFFDWWYDY---GKDNFLF---WIGYSSHIVMTNPKQL 89
            |:..|....|::|   .:....:.:.|..::|..|.   ....|.|   |....:.:|..:|:.:
plant    58 KKHQGMPVWPLVG---MLPSLISAVRSNIYEWLSDVLISQNGTFRFRGPWFSTLNCVVTCDPRNV 119

  Fly    90 EYILNSQQLIQ------KSTIYDLLHPWLGHGLLTSFGSKWHKHRKMITPSFH---FNIL--QDF 143
            |::|.::..|.      :.|:.||    ||.|:..:....|.:.||..:..||   |..|  |..
plant   120 EHLLKTRFSIYPKGSYFRETMQDL----LGDGIFNTDDGTWQRQRKAASVEFHSAKFRQLTSQSL 180

  Fly   144 HEVMN-------ENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVICDTAMGVPINAMEQRDSSI 201
            ||:::       |.|.|              ||.|:....||.|.:|..|.||....:..:...|
plant   181 HELVHNRLLPVLETSGK--------------IDLQDILLRLTFDNVCMIAFGVDPGCLSPKLPEI 231

  Fly   202 VQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKTLKTLQDFTYDIIEKRVYALQNGGSKED 266
            ..|          :||.....:..|..:.|:|  ..|.:::|...|    ||::....||.....
plant   232 PFA----------KAFEDATEATVVRFVMPKF--VWKLMRSLNLGT----EKKLKESINGVDDFA 280

  Fly   267 HDPSLPRKKMAFLDTLLSSTID------------GRPLTRQEIYEEVSTFMFEGHDTTTSGVSFS 319
            .:....|||...|:|.::...|            |:..:.:.:.:....|:..|.||::..:|:.
plant   281 EEVIRTRKKEMSLETEIAKRPDLLTIFMGLRDENGQKFSDKFLRDICVNFILAGRDTSSVALSWF 345

  Fly   320 VYLLSRHPDVQRKLYREQCEVMGH-----DMNRSVSF------QEIAKMKYLDLFIKEAQRVYPS 373
            .:|:.::|:|:.|:....|:::..     |..:::.:      :||.||.||...:.|..|:|||
plant   346 FWLIEKNPEVEEKIMMGICKILEQRVDHGDTKKNMEYEPVFRPEEIKKMDYLQAALSETLRLYPS 410

  Fly   374 VPFIGRYCDKDYDI--NGSIVPKGTTLNLALILLGYNDRIF-KDPHHFRPERFEEE----KPAPF 431
            ||...:...:| |:  :|:.:.||..:..|:..:|..:.|: ||...|:|||:..:    ..:.:
plant   411 VPVDHKEVLED-DVFPDGTKLKKGEKVIYAIYAMGRMETIWGKDCREFKPERWLRDGRYMSESAY 474

  Fly   432 EYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKREA 496
            ::..|:.|||.|:|:.||..:::.|.:.::..::|  .||                       :.
plant   475 KFTAFNGGPRLCLGKDFAYYQMRYVAAAIIYRYKV--RVD-----------------------DK 514

  Fly   497 GRHKYDPILSAVLTLKSDNGLHLRLRER 524
            |.||.:|.::  ||:...:||.:.:.:|
plant   515 GGHKVEPKMA--LTMYMKHGLKVNMVKR 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	p450	35..468	CDD:278495	112/486 (23%)
AT5G08250	NP_001330676.1	CYP86A	98..533	CDD:410687	114/496 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920