DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4e3 and CYP96A9

DIOPT Version :9

Sequence 1:	NP_523527.1	Gene:	Cyp4e3 / 34291	FlyBaseID:	FBgn0015035	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_195658.3	Gene:	CYP96A9 / 830103	AraportID:	AT4G39480	Length:	516	Species:	Arabidopsis thaliana

Alignment Length:	591	Identity:	135/591 - (22%)
Similarity:	227/591 - (38%)	Gaps:	147/591 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LAVLALLVLP------LITLVYFERKASQRRQLLKEFNGPTPVPILGNANRIGKNPAEILSTFFD 61
            :|:::||.:.      ||..::...|...|..|       |..|:||..      |.  |.|...
plant     1 MALVSLLEISIAFFCFLIFRIFLISKKPHRSFL-------TNWPLLGML------PG--LLTVLP 50

  Fly    62 WWYDY-------GKDNFLF---WIGYSSHIVMTNPKQLEYILNSQ-QLIQKSTIYDLLHPWLGHG 115
            ..||:       |..|:||   ::|....:...:|..:.:|::|. ....|.|.:..|...||.|
plant    51 RVYDFITEVLEDGNLNYLFIGPFLGGIDMLFTVDPANIHHIMSSNFANYPKGTEFKKLFDVLGDG 115

  Fly   116 LLTSFGSKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAG-----------DTIID 169
            :..:....|...||......:....|.|         ...|.|.|...|           ..::|
plant   116 IFNADSDLWKDLRKSSQSMMNHPDFQRF---------SLATSLSKLEKGLVPLLDHVAKEKLVVD 171

  Fly   170 FQEHANYLTLDVICDTAMGVPIN--AMEQRDSSIVQAFRDMCYNINMRAFHP--FKRSNRVFSLT 230
            .|:.....|.|.....|.|....  ::|..:....:|..|....|..|.|.|  ..:..|:..:.
plant   172 LQDVFQRFTFDTTFVLATGYDPGCLSVEMPEIEFARALDDAEEAIFYRHFKPEVVWKMQRLIGVG 236

  Fly   231 PEFSAYQKTLKTLQDFTYDIIEKRVYALQNG------GSKEDH-----DPSLPRKKMAFLDTLLS 284
            .|...                 ||.:|:.:.      .||.|.     |.|..:      |.|:|
plant   237 AELKL-----------------KRAHAIFDRVCSKCIASKRDEISQGIDSSSSK------DLLMS 278

  Fly   285 S-TIDG------RPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMG 342
            | .:|.      .|...:.:.:.:.:||..|.|||.|.:::..:||..:.:...|: |::.....
plant   279 SINVDTTKYKLLNPSDDRFLRDTILSFMLAGRDTTGSALTWFFWLLCNNQEAMTKI-RQEINTNL 342

  Fly   343 HDMNR----SVSF-------QEIAKMKYLDLFIKEAQRVYPSVPFIGRYCDK-DYDINGSIVPKG 395
            ...|:    |||:       ||:.|:.||...:.||.|:||.|||..:...| |...:|..|...
plant   343 FPRNKTDDGSVSYDSDSFNPQEVKKLVYLHGAVCEALRLYPPVPFNHKSPAKPDVLPSGHKVKAN 407

  Fly   396 TTLNLALILLGYNDRIF-KDPHHFRPERFEEE------KPAPFEYLPFSAGPRNCIGQKFALLEL 453
            :.:...|..||....:: :|...|:|||:..|      :|: :::|.|:||||.|:|::.|:.::
plant   408 SRILFCLYSLGRMKSVWGEDAMEFKPERWISESGRSVHEPS-YKFLSFNAGPRTCLGKEVAMTQM 471

  Fly   454 KTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKREAGRHKYDPILSAVLTLKSDNGLH 518
            |||..|:::::::              |...|             ||..|..|.:|.:|  :||.
plant   472 KTVAVKIIQNYDI--------------NVVEG-------------HKIKPAPSVILHMK--HGLK 507

  Fly   519 LRLRER 524
            :.:.:|
plant   508 VTVSKR 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	p450	35..468	CDD:278495	116/495 (23%)
CYP96A9	NP_195658.3	p450	1..513	CDD:386267	134/589 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H111093
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010