DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4e3 and CYP705A1

DIOPT Version :9

Sequence 1:	NP_523527.1	Gene:	Cyp4e3 / 34291	FlyBaseID:	FBgn0015035	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_193268.3	Gene:	CYP705A1 / 827199	AraportID:	AT4G15330	Length:	513	Species:	Arabidopsis thaliana

Alignment Length:	521	Identity:	106/521 - (20%)
Similarity:	197/521 - (37%)	Gaps:	124/521 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VLALLVLPLITLVYFERKASQRRQLLKEFNGPTPVPILGN-----ANRIGKNPAEILSTFFDWWY 64
            ::.|....||:...|.:|......||.   .|..:||:|:     :..|.|:..::.|.:
plant    14 IILLCSFSLISYFVFFKKPKVNFDLLP---SPPSLPIIGHLHLLLSTLIHKSLQKLSSKY----- 70

  Fly    65 DYGKDNFLFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDL---------------LHPWLGH 114
                       |...|:.:.|   :.:||.|..    |..|::               :...|..
plant    71 -----------GPLLHLRIFN---IPFILVSSD----SLAYEIFRDHDVNVSSRGVGAIDESLAF 117

  Fly   115 G----LLTSFGSKWHKHRKMITPSFHFNIL--------QDFHEVMNENSAKFMTQL-KKASAGDT 166
            |    :...:|..|...:|:|..    .:|        |||.   :|...:|..:| .||...::
plant   118 GSSGFIQAPYGDYWKFMKKLIAT----KLLGPQPLVRSQDFR---SEELERFYKRLFDKAMKKES 175

  Fly   167 IIDFQEHANYL--TLDVIC-DTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFS 228
            ::..:|.:.::  :|..:| ..:..|..|.:|                             |:..
plant   176 VMIHKEASRFVNNSLYKMCTGRSFSVENNEVE-----------------------------RIME 211

  Fly   229 LTPEFSA----------YQKTLKTLQDFTYD----IIEKRVYALQNGGSKEDHDPSLPRKKMAFL 279
            ||.:..|          ::|.|:.|....:.    ::.:|...|......|..:.....:...|:
plant   212 LTADLGALSQKFFVSKMFRKLLEKLGISLFKTEIMVVSRRFSELVERILIEYEEKMDGHQGTQFM 276

  Fly   280 DTLLSSTIDGR---PLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVM 341
            |.||::..|..   .:||..|...::.|.....|.::..:.:::..:..:.::..||..|...|:
plant   277 DALLAAYRDENTEYKITRSHIKSLLTEFFIGAADASSIAIQWAMADIINNREILEKLREEIDSVV 341

  Fly   342 GHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCDKDYDINGSIVPKGTTLNLALILLG 406
            |  ..|.|...::..:.||...:||..|::|..|.:.|...:..:|.|..|||.|||.:....:.
plant   342 G--KTRLVQETDLPNLPYLQAVVKEGLRLHPPTPLVVREFQEGCEIGGFFVPKNTTLIVNSYAMM 404

  Fly   407 YNDRIFKDPHHFRPERF-------EEEKPAPFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSF 464
            .:...::||..|:||||       |::|.....:|||.:|.|.|.|.....:.:.|.|..:|:.|
plant   405 RDPDSWQDPDEFKPERFLASLSREEDKKEKILNFLPFGSGRRMCPGSNLGYIFVGTAIGMMVQCF 469

  Fly   465 E 465
            :
plant   470 D 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	p450	35..468	CDD:278495	99/491 (20%)
CYP705A1	NP_193268.3	CYP93	71..499	CDD:410748	92/445 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000