DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4e3 and BAS1

DIOPT Version :9

Sequence 1:	NP_523527.1	Gene:	Cyp4e3 / 34291	FlyBaseID:	FBgn0015035	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_180239.1	Gene:	BAS1 / 817212	AraportID:	AT2G26710	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	493	Identity:	128/493 - (25%)
Similarity:	220/493 - (44%)	Gaps:	60/493 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VLALLVLPLITLVYFERKASQRRQLLKEFNGPTPVPILGNANRI-------GKNP--------AE 54
            :|:|:::..::|:::..:..:.....:...||.....:||...:       ..:|        ..
plant    19 ILSLVIVKGMSLLWWRPRKIEEHFSKQGIRGPPYHFFIGNVKELVGMMLKASSHPMPFSHNILPR 83

  Fly    55 ILSTFFDWWYDYGKDNFLFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLLTS 119
            :||.:..|...||. .||.|.|.:..:.:.:|..:..|.:..:..:|:..:.|:....|.|||:.
plant    84 VLSFYHHWRKIYGA-TFLVWFGPTFRLTVADPDLIREIFSKSEFYEKNEAHPLVKQLEGDGLLSL 147

  Fly   120 FGSKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQL------KKASAGDTIIDFQEHANYLT 178
            .|.||..|||:|:|:||...|:....|:    .|.:|.:      |.:..|:..:|..|....||
plant   148 KGEKWAHHRKIISPTFHMENLKLLVPVV----LKSVTDMVDKWSDKLSENGEVEVDVYEWFQILT 208

  Fly   179 LDVICDTAMGVPINAMEQRDSSIVQAFR------DMCYNINMRAFHPFKRSNRVFSLTPEFSAYQ 237
            .|||..||.|     ....|...|  ||      .:|.....:.|.|   ..|.|.......::
plant   209 EDVISRTAFG-----SSYEDGRAV--FRLQAQQMLLCAEAFQKVFIP---GYRFFPTRGNLKSW- 262

  Fly   238 KTLKTLQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLLSSTIDGRPLTRQEIYEEVS 302
            |..|.::.....:||:|.....:|..:|..:|:        ...||...|..:.:|.|:|.||..
plant   263 KLDKEIRKSLLKLIERRRQNAIDGEGEECKEPA--------AKDLLGLMIQAKNVTVQDIVEECK 319

  Fly   303 TFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQE-IAKMKYLDLFIKE 366
            :|.|.|..||::.::::..|||.||:.|.|...|...|.|   :|.|..:: :.|:|.|.:.:.|
plant   320 SFFFAGKQTTSNLLTWTTILLSMHPEWQAKARDEVLRVCG---SRDVPTKDHVVKLKTLSMILNE 381

  Fly   367 AQRVYPSVPFIGRYCDKDYDINGSIVPKGTTLNLALILLGYNDRIF-KDPHHFRPERFEEEKPA- 429
            :.|:||.:....|....|..:.|..:|.||.|.:.:|.:.::..|: .|.:.|.|.||.:..|.
plant   382 SLRLYPPIVATIRRAKSDVKLGGYKIPCGTELLIPIIAVHHDQAIWGNDVNEFNPARFADGVPRA 446

  Fly   430 ---PFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSF 464
               |..::||..|.|.||||..|:|:.|..::.:::.|
plant   447 AKHPVGFIPFGLGVRTCIGQNLAILQAKLTLAVMIQRF 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	p450	35..468	CDD:278495	125/463 (27%)
BAS1	NP_180239.1	CYP734	85..509	CDD:410732	120/427 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.860