Protein Alignment Cyp4e3 and cyp17a2

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001099140.1
• Gene: cyp17a2 / 796487
• ZFINID: ZDB-GENE-100822-1
• Length: 495
• Species: Danio rerio
• Alignment Length: 556
• Identity: 128/556 - (23%)
• Similarity: 207/556 - (37%)
• Gaps: 135/556 - (24%)

  Fly     7 ALLVLPLITLVYFERKASQRRQLLKEFNGPTPV--------PILGNANRIGKN-PAEILSTFFDW 62
            |||:| |:.||         |:|| |..|.:.|        |:||:...:..| |..:|.|...
Zfish    12 ALLLL-LLLLV---------RRLL-EGVGSSSVSFPCLPRLPLLGSLLHLRSNLPPHLLFTQLS- 64

  Fly    63 WYDYGKDNFLFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLLTSFGSK---- 123
             ..||.   ||.:....|:.:.   ..|..|..:.|:|:...:......:...|||..|..
Zfish    65 -SQYGP---LFGLYAGPHLTLV---VSEIGLVREVLLQRGREFAGRPKMVTTDLLTQGGKDIAFA 122

  Fly   124 -----WHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVIC 183
                 |..||:::..||         .:..|.|.|..|.:::|:                 |.:|
Zfish   123 DYSPLWKNHRRLVHSSF---------TLFGEGSNKLQTIVQEAA-----------------DSLC 161

  Fly   184 DTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKT---LKTLQD 245
            :     .:.|...:.|.:.........|:..|.         |||     |:||.:   |:|:..
Zfish   162 E-----ELQACRGQSSDLSVVLMRAVTNVICRL---------VFS-----SSYQPSDPELQTVIQ 207

  Fly   246 FTYDIIEKRVYALQNGG------------------SKE--------------DHDPSL-PRKKMA 277
            :...|::    .:..||                  .||              :|..|| |.:...
Zfish   208 YNDGIVQ----TIARGGLVDIFPWLRIFPNKDLKRLKECVSIRDQLLYKKLLEHKKSLTPGEPRD 268

  Fly   278 FLDTLLSSTIDGR----PLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQC 338
            .||.||.....|.    .:|...:....:.....|.:||::.:.:::..|..||.:|.::..|..
Zfish   269 LLDALLIGQQRGSGGADDITEDHVLMTAAEAFGAGVETTSTTLLWTIAFLLHHPQLQERVQAELD 333

  Fly   339 EVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVP-FIGRYCDKDYDINGSIVPKGTTLNLAL 402
            |.:|.|  |.....:...:..||..:.|..|:.|..| .|.....:|..:.|..|||||.:.:.:
Zfish   334 ECVGVD--RPPCLSDRPHLPLLDAVLCEVMRIRPVSPILIPHVAMQDTSLGGHSVPKGTRVLVNM 396

  Fly   403 ILLGYNDRIFKDPHHFRPERFEE---EKPAPFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSF 464
            ..:.::.:.:..|..|.||||.|   :|.....:|||.||||.|:|:..|.:||...:|:.::.|
Zfish   397 WAIHHDPKHWDQPEQFNPERFLEPSGKKKTQSSFLPFGAGPRVCVGESLARIELFLFVSRPLQRF 461

  Fly   465 EV-LPAVDELVSTDGRLNTYLGLAPDEKLKREAGRH 499
            .. .|:...|....||....  |.|:........||
Zfish   462 SFSCPSEASLPDLQGRFGVV--LQPERYTVTVTPRH 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	106/486 (22%)
cyp17a2	NP_001099140.1	CYP17A1	67..489	CDD:410766	106/480 (22%)